适应性随机临床试验的随机不等式概率

Stochastic inequality probabilities for adaptively randomized clinical trials.

作者信息

Cook John D, Nadarajah Saralees

机构信息

Department of Biostatistics and Applied Mathematics, M.D. Anderson Cancer Center, The University of Texas, Houston, Texas 77030, USA.

出版信息

Biom J. 2006 Jun;48(3):356-65. doi: 10.1002/bimj.200510220.

DOI:10.1002/bimj.200510220

PMID:16845901

Abstract

We examine stochastic inequality probabilities of the form P (X > Y) and P (X > max (Y, Z)) where X, Y, and Z are random variables with beta, gamma, or inverse gamma distributions. We discuss the applications of such inequality probabilities to adaptively randomized clinical trials as well as methods for calculating their values.

摘要

我们研究了形如P(X > Y)和P(X > max(Y, Z))的随机不等式概率，其中X、Y和Z是具有贝塔分布、伽马分布或逆伽马分布的随机变量。我们讨论了此类不等式概率在自适应随机临床试验中的应用以及计算其值的方法。