Seale J Paul, Boltri John M, Shellenberger Sylvia, Velasquez Mary M, Cornelius Monica, Guyinn Monique, Okosun Ike, Sumner Heather
Department of Family Medicine, Medical Center of Central Georgia and Mercer University School of Medicine, Macon, Georgia 31206, USA.
J Stud Alcohol. 2006 Sep;67(5):778-84. doi: 10.15288/jsa.2006.67.778.
The aim of this study was to conduct a primary care validation study of a single screening question for alcohol misuse ("When was the last time you had more than X drinks in 1 day?," where X was four for women and X was five for men), which was previously validated in a study conducted in emergency departments.
This cross-sectional study was accomplished by interviewing 625 male and female adult drinkers who presented to five southeastern primary care practices. Patients answered the single question (coded as within 3 months, within 12 months, ever, or never), Alcohol Use Disorders Identification Test (AUDIT), and AUDIT consumption questions (AUDIT-C). Alcohol misuse was defined as either at-risk drinking, identified by a 29-day Timeline Followback interview or a current (past-year) alcohol-use disorder by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria, or both.
Among 625 drinkers interviewed, 25.6% were at-risk drinkers, 21.7% had a current alcohol- use disorder, and 35.2% had either or both conditions. Considering "within the last 3 months" as positive, the sensitivity of the single question was 80% and the specificity was 74%. Chi-square analyses revealed similar sensitivity across ethnic and gender groups; however, specificity was higher in women and whites (p = .0187 and .0421, respectively). Considering "within the last 12 months" as positive increased the question's sensitivity, especially for those with alcohol-use disorders. The area under the receiver operating characteristic curve of the single alcohol screening question (0.79) was slightly lower than for the AUDIT and AUDIT-C, but sensitivity and specificity were similar.
A single question about the last episode of heavy drinking is a sensitive, time-efficient screening instrument that shows promise for increasing alcohol screening in primary care practices.
本研究旨在对一个关于酒精滥用的单一筛查问题(“你上一次一天饮酒超过X杯是在什么时候?”,女性的X为4杯,男性的X为5杯)进行初级保健验证研究,该问题先前已在急诊科进行的一项研究中得到验证。
这项横断面研究通过对前往东南部五家初级保健机构就诊的625名成年男女饮酒者进行访谈来完成。患者回答了这个单一问题(编码为在3个月内、在12个月内、曾经或从不)、酒精使用障碍识别测试(AUDIT)以及AUDIT饮酒量问题(AUDIT-C)。酒精滥用被定义为通过29天时间线追溯访谈确定的危险饮酒,或根据《精神疾病诊断与统计手册》第四版标准确定的当前(过去一年)酒精使用障碍,或两者皆有。
在接受访谈的625名饮酒者中,25.6%为危险饮酒者,21.7%患有当前酒精使用障碍,35.2%患有其中一种或两种情况。将“在过去3个月内”视为阳性时,单一问题的敏感性为80%,特异性为74%。卡方分析显示不同种族和性别群体的敏感性相似;然而,女性和白人的特异性更高(分别为p = 0.0187和0.0421)。将“在过去12个月内”视为阳性提高了该问题的敏感性,尤其是对于患有酒精使用障碍的人。单一酒精筛查问题的受试者工作特征曲线下面积(0.79)略低于AUDIT和AUDIT-C,但敏感性和特异性相似。
一个关于最近一次大量饮酒的单一问题是一种敏感、省时的筛查工具,有望在初级保健机构中增加酒精筛查。