短期克雅氏病中的朊蛋白淀粉样斑块：来自波兰的5例病例的免疫组织化学研究
PrP amyloid plaques in Creutzfeldt-Jakob disease of short duration: immunohistochemical studies of 5 cases from Poland.
作者信息
Liberski P P, Kwiecinski H, Barcikowska M, Mirecka B, Kulczycki J, Kida E, Brown P, Gajdusek D C
机构信息
Dept. Oncology, Medical Academy Lodz, Poland.
出版信息
Eur J Epidemiol. 1991 Sep;7(5):505-10. doi: 10.1007/BF00143130.
PMID:1684757
Abstract
We report here PrP-immunohistochemistry performed on brains from CJD cases from Poland. Only one of five definitive CJD cases exhibited typical PrP-immunoreactive kuru-like plaques and this was case of a short duration. We thus confirm the low frequency of PrP plaques in CJD of Eastern and Central European origin.
摘要
我们在此报告对来自波兰克雅氏病（CJD）病例大脑进行的朊蛋白（PrP）免疫组织化学检测结果。在5例确诊的CJD病例中，只有1例出现了典型的PrP免疫反应性库鲁病样斑块，且该病例病程较短。因此，我们证实了源自东欧和中欧的CJD中PrP斑块的低发生率。
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