Ryan Lori J, Pambuccian Stefan E, Lai Rebecca, Gulbahce H Evin
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Diagn Cytopathol. 2006 Aug;34(8):576-9. doi: 10.1002/dc.20504.
The cytologic findings of a paratracheal metastasis from a malignant sex cord tumor with annular tubules (SCTATs) diagnosed by endoscopic ultrasound guided fine needle aspiration are described. Cytologic features of SCTATs include the presence of highly cellular aspirates forming simple and complex rosette-like structures around central rounded hyaline material, small nucleoli, and prominent nuclear grooves. These cytologic findings are clearly distinct from the poorly formed rosette-like structures of granulosa-cell tumors and are reminiscent of the low-power appearance of the cribriform variant of adenoid cystic carcinoma. The fine needle aspiration cytologic features of only two other cases have been previously described and, to the best of our knowledge, this is the first case reporting the cytologic diagnosis of a distant metastasis of a SCTATs by endoscopic ultrasound-guided fine needle aspiration. In this case, the distinctive and characteristic cytologic features have allowed the proper diagnosis of a distant metastasis of SCTATs.
描述了通过内镜超声引导下细针穿刺诊断的恶性环状小管性索肿瘤（SCTATs）气管旁转移的细胞学发现。SCTATs的细胞学特征包括高细胞性吸出物，形成围绕中央圆形透明物质的简单和复杂的玫瑰花结样结构、小核仁以及明显的核沟。这些细胞学发现与颗粒细胞瘤形成不良的玫瑰花结样结构明显不同，让人联想到腺样囊性癌筛状变型的低倍镜表现。此前仅描述过另外两例的细针穿刺细胞学特征，据我们所知，这是首例通过内镜超声引导下细针穿刺报告SCTATs远处转移的细胞学诊断病例。在该病例中，独特且典型的细胞学特征使得能够正确诊断SCTATs的远处转移。
