Warnock L J, Brown P, Preston F E
Department of Haematology, Royal Hallamshire Hospital, Sheffield, England.
Blood Coagul Fibrinolysis. 1991 Feb;2(1):207-9.
We describe a program GENESRCH which has been written to enable the design of efficient restriction fragment analysis of DNA from patients with hereditary disorders. The program identifies homology of DNA sequences up to 20 base pairs in length, calculates the fragment sizes and indicates the position of enzyme restriction sites within the gene of interest. GENESRCH is written in the BASIC language and will run on any IBM-compatible PC with a parallel printer. A hard disc is recommended for efficient storage and retrieval of data. An example of the use of the program is cited.
我们描述了一个名为GENESRCH的程序，该程序用于对遗传性疾病患者的DNA进行高效的限制性片段分析设计。该程序可识别长度达20个碱基对的DNA序列的同源性，计算片段大小，并指出感兴趣基因内酶切位点的位置。GENESRCH用BASIC语言编写，可在任何带有并行打印机的IBM兼容个人电脑上运行。建议使用硬盘以实现数据的高效存储和检索。文中引用了该程序的一个使用示例。
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