Kretschmer M
Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115.
Biotechniques. 1993 Jun;14(6):996-1001.
A system of programs is presented that turns the HP 48SX calculator into a pocket database for molecular biology with a library of restriction enzymes and plasmids. The operations of the calculator are extended to handle DNA and peptide sequences much like numbers. The software provides a comprehensive system for cloning and includes functions for cutting and ligation, DNA-peptide translation and its reverse, DNA probe design, and codon usage statistics. Since the calculator comes with built-in Kermit protocol, serial port, infrared interface, and sequences are in ASCII code, users can communicate sequences bench-to-bench to other calculators or upload and download them with IBM PC compatible and Macintosh computers.