钝性撞击下肾脏的生物力学反应分析
Analysis of the biomechanical response of kidneys under blunt impact.
作者信息
Schmitt Kai-Uwe, Snedeker Jess G
机构信息
Institute for Biomedical Engineering, Swiss Federal Institute of Technology (ETH) and University of Zurich, Switzerland.
出版信息
Traffic Inj Prev. 2006 Jun;7(2):171-81. doi: 10.1080/15389580500482021.
OBJECTIVE
This study addresses the biomechanical response of isolated kidneys to traumatic insult.
METHODS
Kidneys were subjected to blunt impact by using a freely swinging right cylindrical pendulum. Force-deformation characteristics were derived for 65 impacted adult pig kidneys. Renal injuries were classified by autopsy, and an injury risk analysis was performed. In addition a finite element model that simulated the experiments was implemented.
RESULTS/CONCLUSIONS: The kidneys showed a viscoelastic response. An energy-based injury threshold was identified, with a strain energy density of 21 kJ/m(3) corresponding to a 50-percent risk of renal injury level AIS3 or higher. Finally, the impact tests were simulated using a finite element model of the kidney to investigate relevant injury mechanisms. The model predicted the renal capsule and underlying parenchyma to first fail at an impact energy level of 4.0 J, consistent with experimental results.
目的
本研究探讨离体肾脏对创伤性损伤的生物力学反应。
方法
使用自由摆动的右圆柱形摆锤对肾脏进行钝性撞击。得出了65个受撞击成年猪肾脏的力-变形特性。通过尸检对肾损伤进行分类，并进行损伤风险分析。此外，还建立了模拟实验的有限元模型。
结果/结论：肾脏表现出粘弹性反应。确定了基于能量的损伤阈值，应变能密度为21 kJ/m(3)时，肾损伤达到AIS3级或更高的风险为50%。最后，使用肾脏的有限元模型模拟撞击试验，以研究相关损伤机制。该模型预测肾包膜及其下方的实质在撞击能量为4.0 J时首先失效，与实验结果一致。
Zotero 插件