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输卵管绝育术后继发不孕的体外受精与输卵管再吻合术(绝育逆转)比较

In vitro fertilisation versus tubal reanastomosis (sterilisation reversal) for subfertility after tubal sterilisation.

作者信息

Yossry M, Aboulghar M, D'Angelo A, Gillett W

机构信息

West Midlands Deanery, Obststrics & Gynaecology, 28 Regnt Close, Edgbaston, Birmingham, West Midlands, UK B5 7PL.

出版信息

Cochrane Database Syst Rev. 2006 Jul 19;2006(3):CD004144. doi: 10.1002/14651858.CD004144.pub2.

Abstract

BACKGROUND

Tubal sterilisation is the most popular contraceptive method in the world. Approximately 138 million women of reproductive age have had tubal sterilisation and there is evidence that increasingly younger women are being sterilized. With such large numbers of women choosing this option of birth control, it is clear that even if a small percentage of women later regret the decision, large numbers of women will seek counselling regarding reversal from their physicians.

OBJECTIVES

To compare the efficacy of surgical tubal reanastomosis and in vitro fertilisation in terms of live birth rates. The morbidity and cost-effectiveness of both techniques were also to be compared.

SEARCH STRATEGY

The following databases were searched: Cochrane Menstrual Disorders and Subfertility Review Group Specialised Register, MEDLINE (1966 to 2005), EMBASE (1980 to 2005), and other electronic databases. We handsearched the reference lists of trials, reviews and relevant textbooks; searched abstracts from relevant conferences, and personally communicated with experts in the field.

SELECTION CRITERIA

Randomised and quasi-randomised trials comparing surgical reversal of tubal sterilisation with in vitro fertilisation (IVF). The method of allocation will be assessed and results subgrouped according to whether the trials were randomised or quasi-randomised.

DATA COLLECTION AND ANALYSIS

No trials were found that met the selection criteria.

MAIN RESULTS

No data exist on which to report.

AUTHORS' CONCLUSIONS: There is a need for well-designed controlled clinical trials to compare the efficacy and safety of surgical reversal of tubal sterilisation and IVF in restoring fertility in women seeking pregnancy following tubal sterilisation.

摘要

背景

输卵管绝育术是全球最常用的避孕方法。约有1.38亿育龄妇女接受了输卵管绝育术,且有证据表明,接受绝育手术的女性越来越年轻。鉴于如此多的女性选择这种节育方式,显然即便只有一小部分女性后来对这一决定感到后悔,也会有大量女性就输卵管复通问题向医生咨询。

目的

比较手术输卵管复通术与体外受精在活产率方面的疗效。同时比较这两种技术的发病率及成本效益。

检索策略

检索了以下数据库:Cochrane月经紊乱与生育力低下综述组专业注册库、MEDLINE(1966年至2005年)、EMBASE(1980年至2005年)以及其他电子数据库。我们手工检索了试验、综述及相关教科书的参考文献列表;检索了相关会议的摘要,并与该领域的专家进行了个人交流。

入选标准

比较输卵管绝育术手术复通与体外受精(IVF)的随机和半随机试验。将根据试验是随机还是半随机来评估分配方法并对结果进行分组。

数据收集与分析

未找到符合入选标准的试验。

主要结果

无可报告的数据。

作者结论

需要设计良好的对照临床试验,以比较输卵管绝育术手术复通与IVF在帮助输卵管绝育术后寻求妊娠的女性恢复生育能力方面的疗效和安全性。

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