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门诊环境中针对大麻滥用和/或依赖的心理治疗干预措施。

Psychotherapeutic interventions for cannabis abuse and/or dependence in outpatient settings.

作者信息

Denis C, Lavie E, Fatséas M, Auriacombe M

机构信息

Universite Victor Segalen Bordeaux - Centre Carreire du CHCP, Laboratoire de Psychiatrie, 121 rue de la Bechade, Bordeaux Cedex, European Union 33076.

出版信息

Cochrane Database Syst Rev. 2006 Jul 19(3):CD005336. doi: 10.1002/14651858.CD005336.pub2.

Abstract

BACKGROUND

Cannabis use disorder is the most common illicit substance use disorder in general population. Despite that, only a minority seek assistance from a health professional, but the demand for treatment is now increasing internationally. Trials of treatment have been published but to our knowledge, there is no published systematic review .

OBJECTIVES

To evaluate the efficacy of psychosocial interventions for cannabis abuse or dependence.

SEARCH STRATEGY

We searched the Cochrane Central Register of Trials (CENTRAL) The Cochrane Library Issue 3, 2004; MEDLINE (January 1966 to August 2004), PsycInfo (1985 to October 2004), CINAHL (1982 to October 2004), Toxibase (until September 2004) and reference lists of articles. We also contacted researchers in the field.

SELECTION CRITERIA

All randomized controlled studies examining a psychotherapeutic intervention for cannabis dependence or abuse in comparison with a delayed-treatment control group or combinations of psychotherapeutic interventions.

DATA COLLECTION AND ANALYSIS

Two authors independently assessed trial quality and extracted data

MAIN RESULTS

Six trials involving 1297 people were included. Five studies took place in the United States, one in Australia. Studies were not pooled in meta-analysis because of heterogeneity. The six included studies suggested that counseling approaches might have beneficial effects for the treatment of cannabis dependence. Group and individual sessions of cognitive behavioral therapy (CBT) had both efficacy for the treatment of cannabis dependence and associated problems, CBT produced better outcomes than a brief intervention when CBT was delivered in individual sessions. Two studies suggested that adding voucher-based incentives may enhance treatment when used in combination with other effective psychotherapeutic interventions. Abstinence rates were relatively small overall but favored the individual CBT 9-session (or more) condition. All included trials reported a statistically significant reductions in frequency of cannabis use and dependence symptoms. But other measures of problems related to cannabis use were not consistently different.

AUTHORS' CONCLUSIONS: The included studies were too heterogenous and could not allow to draw up a clear conclusion. The studies comparing different therapeutic modalities raise important questions about the duration, intensity and type of treatment. The generalizability of findings is also unknown because the studies have been conducted in a limited number of localities with fairly homogenous samples of treatment seekers. However, the low abstinence rate indicated that cannabis dependence is not easily treated by psychotherapies in outpatient settings.

摘要

背景

大麻使用障碍是普通人群中最常见的非法物质使用障碍。尽管如此,只有少数人会寻求健康专业人员的帮助,但目前国际上对治疗的需求正在增加。关于治疗的试验已经发表,但据我们所知,尚无已发表的系统评价。

目的

评估心理社会干预对大麻滥用或依赖的疗效。

检索策略

我们检索了Cochrane临床试验中心注册库(CENTRAL)(《Cochrane图书馆》2004年第3期)、MEDLINE(1966年1月至2004年8月)、PsycInfo(1985年至2004年10月)、CINAHL(1982年至2004年10月)、Toxibase(截至2004年9月)以及文章的参考文献列表。我们还联系了该领域的研究人员。

选择标准

所有随机对照研究,比较针对大麻依赖或滥用的心理治疗干预与延迟治疗对照组,或心理治疗干预的组合。

数据收集与分析

两位作者独立评估试验质量并提取数据。

主要结果

纳入了6项涉及1297人的试验。5项研究在美国进行,1项在澳大利亚进行。由于异质性,研究未进行荟萃分析。纳入的6项研究表明,咨询方法可能对大麻依赖的治疗有有益效果。认知行为疗法(CBT)的团体和个体治疗对大麻依赖及相关问题均有疗效,当以个体治疗形式提供CBT时,其效果优于简短干预。两项研究表明,在与其他有效的心理治疗干预联合使用时,增加基于代金券的激励措施可能会增强治疗效果。总体戒断率相对较低,但个体CBT 9节(或更多)疗程的情况更有利。所有纳入试验均报告大麻使用频率和依赖症状在统计学上有显著降低。但与大麻使用相关的其他问题指标并无一致差异。

作者结论

纳入的研究异质性太大,无法得出明确结论。比较不同治疗方式的研究提出了关于治疗持续时间、强度和类型的重要问题。由于研究是在有限数量的地区对样本相当同质的寻求治疗者进行的,研究结果的可推广性也未知。然而,低戒断率表明,在门诊环境中,心理治疗难以治疗大麻依赖。

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