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川崎病患者的冠状动脉搭桥术:诗里拉吉医院的经验。

Coronary artery bypass graft in Kawasaki disease patients: Siriraj experience.

作者信息

Chanthong Prakul, Sriyoschati Somchai, Durongpisitkul Kritvikrom, Soongswang Jarupim, Laohaprasitiporn Duangmanee, Nana Apichart

机构信息

Division of cardiology, Department of Pediatrics, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2005 Nov;88 Suppl 8:S197-202.

Abstract

Kawasaki disease (KD) is an acute systemic vasculitis. It is one of the most common acquired heart diseases in children. Its important acute complication is coronary artery aneurysm. Although most of these aneurysms resolved overtime but some never did. Coronary artery stenosis and myocardial insufficiency or infarction are late complications. Coronary artery bypass graft (CABG) and catheter intervention are the treatment for these patients. We report our first five cases of Kawasaki patients with myocardial insufficiency who underwent CABG at Siriraj Hospital. Patients' ages ranged from 3.3 to 14.4 years old. Only two patients (40%) had angina. Internal thoracic artery was used as a bypass graft in most patients and postoperative course was uneventful. Coronary bypass operation is a safe and reliable surgical modality for coronary artery sequelae in children with Kawasaki disease. A long-term follow-up is necessary to study the long-term outcome of bypass.

摘要

川崎病(KD)是一种急性全身性血管炎。它是儿童最常见的后天性心脏病之一。其重要的急性并发症是冠状动脉瘤。虽然这些动脉瘤大多会随时间消退,但有些则不会。冠状动脉狭窄和心肌功能不全或梗死是晚期并发症。冠状动脉搭桥术(CABG)和导管介入是这些患者的治疗方法。我们报告了在诗里拉吉医院接受CABG的首例五例川崎病合并心肌功能不全患者。患者年龄在3.3至14.4岁之间。只有两名患者(40%)有胸痛症状。大多数患者使用胸廓内动脉作为搭桥血管,术后过程顺利。冠状动脉搭桥手术是治疗川崎病患儿冠状动脉后遗症的一种安全可靠的手术方式。需要进行长期随访以研究搭桥手术的长期效果。

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