Qu Ling-bo, Wang Ling, Yang Ran, Chen Xiao-lan, Li Ping
Department of Chemistry, Zhengzhou University, China.
Yao Xue Xue Bao. 2006 Apr;41(4):352-7.
To study the interaction mechanism of bovine serum albumin (BSA) with luteolin and apigenin.
Fluorescence quenching method and non-radioactive energy transfer theory were used.
The binding constants at different temperature were determined and the quenching mechanism of them were suggested as static quenching. The transfer efficiency of energy and distance between BSA and luteolin or apigenin were investigated according to the mechanism of the Förster energy transference.
The interaction between them seems to be strong and the binding force were mainly hydrophobic force. B(3')-OH,B(4')-OH strengthened the interaction of flavonoids and BSA.
研究牛血清白蛋白（BSA）与木犀草素和芹菜素的相互作用机制。
采用荧光猝灭法和非辐射能量转移理论。
测定了不同温度下的结合常数，并认为它们的猝灭机制为静态猝灭。根据Förster能量转移机制研究了BSA与木犀草素或芹菜素之间的能量转移效率和距离。
它们之间的相互作用似乎很强，结合力主要是疏水作用力。B（3'）-OH、B（4'）-OH增强了黄酮类化合物与BSA的相互作用。
