Sun Tao, Walsh Christopher A
Department of Cell and Developmental Biology, Cornell University Weill Medical College, Box 60, W820A, 1300 York Avenue, New York 10021, USA.
Nat Rev Neurosci. 2006 Aug;7(8):655-62. doi: 10.1038/nrn1930.
In the human brain, distinct functions tend to be localized in the left or right hemispheres, with language ability usually localized predominantly in the left and spatial recognition in the right. Furthermore, humans are perhaps the only mammals who have preferential handedness, with more than 90% of the population more skillful at using the right hand, which is controlled by the left hemisphere. How is a distinct function consistently localized in one side of the human brain? Because of the convergence of molecular and neurological analysis, we are beginning to consider the puzzle of brain asymmetry and handedness at a molecular level.
在人类大脑中,不同的功能往往定位在左半球或右半球,语言能力通常主要定位在左侧,而空间识别能力则在右侧。此外,人类可能是唯一有偏好性利手的哺乳动物,超过90%的人更擅长使用右手,而右手是由左半球控制的。一种独特的功能是如何始终如一地定位在人类大脑的一侧的呢?由于分子分析和神经学分析的结合,我们开始在分子水平上思考大脑不对称和利手性的谜题。