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壶腹肿瘤的治疗方法。

Therapeutic approach to tumors of the ampulla of Vater.

作者信息

Kobayashi Akihiko, Konishi Masaru, Nakagohri Toshio, Takahashi Shinichiro, Kinoshita Taira

机构信息

Surgery Division, National Cancer Center Hospital East, Kashiwa City, Chiba, Japan.

出版信息

Am J Surg. 2006 Aug;192(2):161-4. doi: 10.1016/j.amjsurg.2006.05.002.

Abstract

BACKGROUND/AIM: Indications for local resection for tumors of the ampulla of Vater have not been established. The present study evaluated suitable treatments for tumors of the papilla of Vater.

PATIENTS AND METHODS

Clinicopathological factors were reviewed for 53 patients with tumors of the ampulla of Vater treated between February 1993 and August 2003.

RESULTS

Of 53 patients, 41 were treated surgically. Local resection was performed in 7 of these 41 patients, with a histologically involved margin evident in 4 patients. Lymph node metastasis was identified in 20 patients who received radical resection, including 1 patient with pT1 cancer.

CONCLUSION

Given the presence of some positive surgical margins, local resection is indicated as a therapeutic approach to tumors of the papilla of Vater only for benign tumors or some malignant tumors that cannot undergo pancreaticoduodenectomy (PD).

摘要

背景/目的:关于 Vater 壶腹肿瘤局部切除术的适应证尚未确定。本研究评估了 Vater 乳头肿瘤的合适治疗方法。

患者与方法

回顾性分析了 1993 年 2 月至 2003 年 8 月期间接受治疗的 53 例 Vater 壶腹肿瘤患者的临床病理因素。

结果

53 例患者中,41 例行手术治疗。这 41 例患者中有 7 例行局部切除术,其中 4 例组织学切缘阳性。20 例行根治性切除术的患者出现淋巴结转移,其中 1 例为 pT1 期癌。

结论

鉴于存在一些手术切缘阳性的情况,局部切除术仅适用于良性肿瘤或一些无法行胰十二指肠切除术(PD)的恶性肿瘤,作为 Vater 乳头肿瘤的一种治疗方法。

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