Department of Surgery, Ome Municipal General Hospital, 16-5, Higashi Ome 4-chome, Ome-shi, Tokyo, 198-0042, Japan.
World J Surg Oncol. 2010 May 20;8:41. doi: 10.1186/1477-7819-8-41.
Gallbladder perforation is a rare clinical condition, which mostly occurs following acute cholecystitis associated with cholelithiasis. A tumor of the ampulla of Vater causes gradually progressive symptoms, and is rarely associated with perforation of the gallbladder.
A 56-year-old man with carcinoma of the ampulla of Vater presented with spontaneous gallbladder perforation and localized bile peritonitis. He complained of right upper abdominal pain, and laparotomy revealed perforation of the gallbladder with no gallstones. Postoperative upper gastrointestinal endoscopy demonstrated a slightly enlarged duodenal papilla, and biopsy revealed adenocarcinoma of the ampulla. Pylorus-preserving pancreaticoduodenectomy was performed subsequently.
Ampullary carcinoma can be associated with gallbladder perforation and present with acute manifestations. Immediate surgical treatment is required for this condition.
胆囊穿孔是一种罕见的临床情况，主要发生在伴有胆石症的急性胆囊炎之后。壶腹肿瘤引起逐渐进展的症状，很少与胆囊穿孔有关。
一位 56 岁男性，患有 Vater 壶腹癌，表现为自发性胆囊穿孔和局限性胆汁性腹膜炎。他主诉右上腹痛，剖腹探查发现胆囊穿孔且无胆石。术后上消化道内镜检查显示十二指肠乳头稍肿大，活检显示壶腹腺癌。随后行保留幽门的胰十二指肠切除术。
壶腹癌可与胆囊穿孔相关，并表现出急性表现。这种情况需要立即进行手术治疗。
