Shin Seung Yong, Bajpai Vivek K, Kim Hak Ryul, Kang Sun Chul
Division of Food, Biological and Chemical Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea.
Int J Food Microbiol. 2007 Jan 25;113(2):233-6. doi: 10.1016/j.ijfoodmicro.2006.05.020. Epub 2006 Jul 24.
The antimicrobial activity of bioconversion extracts of EPA and DHA against a range of foodborne pathogenic bacteria was investigated. The bioconverted EPA and DHA exhibited antibacterial activities against four gram-positive bacteria, Bacillus subtilis, Listeria monocytogenes, Staphylococcus aureus (ATCC 6538) and S. aureus (KCTC 1916) and seven gram-negative bacteria, Enterobacter aerogenes, Escherichia coli, E. coli O157:H7, E. coli O157:H7 (human), Pseudomonas aeruginosa, Salmonella enteritidis and S. typhimurium. The growth inhibition by both bioconverted EPA and DHA was similar against gram-positive bacteria, while the bioconverted extract of DHA was more effective than EPA against gram-negative bacteria as determined by minimum inhibitory concentration.
研究了 EPA 和 DHA 生物转化提取物对一系列食源性病原体细菌的抗菌活性。生物转化的 EPA 和 DHA 对四种革兰氏阳性菌,即枯草芽孢杆菌、单核细胞增生李斯特菌、金黄色葡萄球菌(ATCC 6538)和金黄色葡萄球菌(KCTC 1916)以及七种革兰氏阴性菌,即产气肠杆菌、大肠杆菌、大肠杆菌 O157:H7、大肠杆菌 O157:H7(人源)、铜绿假单胞菌、肠炎沙门氏菌和鼠伤寒沙门氏菌均表现出抗菌活性。通过最小抑菌浓度测定,生物转化的 EPA 和 DHA 对革兰氏阳性菌的生长抑制作用相似,而生物转化的 DHA 提取物对革兰氏阴性菌的效果比 EPA 更有效。