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生物转化的二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)对食源性病原体的抗菌活性。

Antibacterial activity of bioconverted eicosapentaenoic (EPA) and docosahexaenoic acid (DHA) against foodborne pathogenic bacteria.

作者信息

Shin Seung Yong, Bajpai Vivek K, Kim Hak Ryul, Kang Sun Chul

机构信息

Division of Food, Biological and Chemical Engineering, Daegu University, Gyeongsan 712-714, Republic of Korea.

出版信息

Int J Food Microbiol. 2007 Jan 25;113(2):233-6. doi: 10.1016/j.ijfoodmicro.2006.05.020. Epub 2006 Jul 24.

Abstract

The antimicrobial activity of bioconversion extracts of EPA and DHA against a range of foodborne pathogenic bacteria was investigated. The bioconverted EPA and DHA exhibited antibacterial activities against four gram-positive bacteria, Bacillus subtilis, Listeria monocytogenes, Staphylococcus aureus (ATCC 6538) and S. aureus (KCTC 1916) and seven gram-negative bacteria, Enterobacter aerogenes, Escherichia coli, E. coli O157:H7, E. coli O157:H7 (human), Pseudomonas aeruginosa, Salmonella enteritidis and S. typhimurium. The growth inhibition by both bioconverted EPA and DHA was similar against gram-positive bacteria, while the bioconverted extract of DHA was more effective than EPA against gram-negative bacteria as determined by minimum inhibitory concentration.

摘要

研究了 EPA 和 DHA 生物转化提取物对一系列食源性病原体细菌的抗菌活性。生物转化的 EPA 和 DHA 对四种革兰氏阳性菌,即枯草芽孢杆菌、单核细胞增生李斯特菌、金黄色葡萄球菌(ATCC 6538)和金黄色葡萄球菌(KCTC 1916)以及七种革兰氏阴性菌,即产气肠杆菌、大肠杆菌、大肠杆菌 O157:H7、大肠杆菌 O157:H7(人源)、铜绿假单胞菌、肠炎沙门氏菌和鼠伤寒沙门氏菌均表现出抗菌活性。通过最小抑菌浓度测定,生物转化的 EPA 和 DHA 对革兰氏阳性菌的生长抑制作用相似,而生物转化的 DHA 提取物对革兰氏阴性菌的效果比 EPA 更有效。

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