Endometrial disorders in patients with peritoneal serous papillary carcinoma.
作者信息
Bafghi Abdi, Zafrani Yaelle, Pautier Patricia, Lhommé Catherine, Duvillard Pierre, Castaigne Damienne, Haie-Meder Chistine, Morice Philippe
机构信息
Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France.
出版信息
Eur J Obstet Gynecol Reprod Biol. 2007 Sep;134(1):101-4. doi: 10.1016/j.ejogrb.2006.06.011. Epub 2006 Jul 24.
BACKGROUND
The purpose of this study was to evaluate the incidence rate of endometrial disease, particularly endometrial carcinoma, in patients with primary peritoneal serous papillary carcinoma (PSPC).
METHODS
Retrospective review of clinical and histological data from 32 women undergoing surgery (with hysterectomy) for stage III or IV PSPC.
RESULTS
Six patients underwent primary debulking surgery and 26 underwent interval debulking surgery after 3 or 4 courses of platinum-based chemotherapy. Six patients (18%) had endometrial disease (hyperplasia in four). Two patients had endometrioid adenocarcinoma of the uterine body (stage IA grade 1 in one case, and stage IB grade 1 in the other) associated with the PSPC.
CONCLUSIONS
Endometrial carcinoma of the uterine body may be associated with PSPC (6% cases in the present series). This result suggests that systematic hysterectomy should be performed at the time of debulking surgery in PSPC, even in the absence of peritoneal spread within pelvic cavity.
Zotero 插件