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升主动脉成形术复位:中期随访及再扩张的预测因素

Reduction ascending aortoplasty: midterm follow-up and predictors of redilatation.

作者信息

Polvani Gianluca, Barili Fabio, Dainese Luca, Topkara Veli K, Cheema Faisal H, Penza Eleonora, Ferrarese Sandro, Parolari Alessandro, Alamanni Francesco, Biglioli Paolo

机构信息

Department of Cardiovascular Surgery, Centro Cardiologico Monzino, University of Milan, Milan, Italy.

出版信息

Ann Thorac Surg. 2006 Aug;82(2):586-91. doi: 10.1016/j.athoracsur.2006.03.025.

Abstract

BACKGROUND

Reduction ascending aortoplasty is an alternative procedure to the replacement of the ascending aorta in case of ascending aorta aneurysm without aortic root involvement. This study was designed to evaluate the midterm follow-up of aortoplasty and to determine predictors of redilatation.

METHODS

From January 1, 1998, to April 30, 2005, 68 patients with dilatation of the ascending aorta underwent unsupported reduction aortoplasty in combination with other cardiac procedures. All patients underwent associated surgical procedures. Sixty patients (88.2%) underwent associated aortic valve replacement. Cumulative follow-up time was 191.4 patient-years and was 100% complete. Median follow-up time was 2.5 years, and mean follow-up time was 2.9 +/- 1.7 years (range, 0.4 to 6.3 years).

RESULTS

The overall perioperative mortality rate was 1.5%. Overall survival estimates at 3 and 6 years were 93.3% +/- 4.5% and 89.3% +/- 5.9%, respectively. The actuarial freedom from cardiac-related death at 3 and 6 years was 100% and 95.7% +/- 4.3%, respectively. Ascending aorta redilatation occurred in 5 patients (7.5%). The actuarial freedom from redilatation at 3 and 6 years was 97.7% +/- 2.3% and 79.8% +/- 8.4%, respectively. The actuarial freedom from reoperation at 3 and 6 years was 100% and 86.3% +/- 7.5%, respectively. Only preoperative diameter was a significant predictor of redilatation using multivariate stepwise logistic regression analysis.

CONCLUSIONS

Unsupported reduction aortoplasty is a safe and effective technique with low mortality, low morbidity, and rare late complications for selected chronic aneurysm of the ascending aorta with diameter less than 55 mm.

摘要

背景

对于升主动脉瘤且不累及主动脉根部的情况,升主动脉缩窄成形术是升主动脉置换术的一种替代手术。本研究旨在评估主动脉缩窄成形术的中期随访情况并确定再扩张的预测因素。

方法

从1998年1月1日至2005年4月30日,68例升主动脉扩张患者在接受其他心脏手术的同时接受了非支撑性升主动脉缩窄成形术。所有患者均接受了相关的外科手术。60例患者(88.2%)接受了相关的主动脉瓣置换术。累积随访时间为191.4患者年,随访完整率为100%。中位随访时间为2.5年,平均随访时间为2.9±1.7年(范围为0.4至6.3年)。

结果

围手术期总死亡率为1.5%。3年和6年的总体生存率估计分别为93.3%±4.5%和89.3%±5.9%。3年和6年与心脏相关死亡的无事件生存率分别为100%和95.7%±4.3%。5例患者(7.5%)出现升主动脉再扩张。3年和6年的无再扩张生存率分别为97.7%±2.3%和79.8%±8.4%。3年和6年的无再次手术生存率分别为100%和86.3%±7.5%。使用多变量逐步逻辑回归分析,仅术前直径是再扩张的显著预测因素。

结论

对于直径小于55mm的特定慢性升主动脉瘤,非支撑性升主动脉缩窄成形术是一种安全有效的技术,死亡率低、发病率低且晚期并发症罕见。

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