Feindt Peter, Litmathe Jens, Börgens Adina, Boeken Udo, Kurt Muhammed, Gams Emmeran
Department of Thoracic and Cardiovascular Surgery, Heinrich-Heine-University Hospital, Düsseldorf, Germany.
Eur J Cardiothorac Surg. 2007 Apr;31(4):614-7. doi: 10.1016/j.ejcts.2007.01.028. Epub 2007 Feb 16.
Enlargement of the ascending aorta is often combined with valvular, coronary, or other cardiac diseases. Reduction aortoplasty can be an optional therapy; however, indications regarding the diameter of aorta, the history of dilatation (poststenosis, bicuspid aortic valve), or the intraoperative management (wall excision, reduction suture, external reinforcement) are not established.
In a retrospective study between 1997 and 2005, we investigated 531 patients operated for aneurysm or ectasia of the ascending aorta (diameter: 45-76mm). Of these, in 50 patients, size-reducing ascending aortoplasty was performed. External reinforcement with a non-coated dacron prosthesis was added in order to stabilize the aortic wall.
Aortoplasty was associated with aortic valve replacement in 47 cases (35 mechanical vs 12 biological), subvalvular myectomy in 29 cases, and CABG in 13 cases. The procedure was performed with low hospital mortality (2%) and a low postoperative morbidity. Computertomographic and echocardiographic diameters were significantly smaller after reduction (55.8+/-9mm down to 40.51+/-6.2mm (CT), p<0.002; 54.1+/-6.7mm preoperatively down to 38.7+/-7.1mm (echocardiography), p<0.002), with stable performance in long-term follow-up (mean follow-up time: 70 months).
As demonstrated in this study, size reduction of the ascending aorta using aortoplasty with external reinforcement is a safe procedure with excellent long-term results. It is a therapeutic option in modern aortic surgery in patients with poststenotic dilatation of the aorta without impairment of the sinotubular junction of the aortic valve and root.
升主动脉扩大常合并瓣膜、冠状动脉或其他心脏疾病。主动脉缩窄成形术可作为一种选择的治疗方法;然而,关于主动脉直径、扩张病史(狭窄后、二叶式主动脉瓣)或术中处理(切除管壁、缩窄缝合、外部加固)的指征尚未确定。
在一项1997年至2005年的回顾性研究中,我们调查了531例行升主动脉瘤或扩张手术的患者(直径:45 - 76mm)。其中,50例患者接受了缩小型升主动脉成形术。为稳定主动脉壁,加用了未涂层的涤纶人工血管进行外部加固。
47例(35例机械瓣置换 vs 12例生物瓣置换)患者在主动脉成形术的同时行主动脉瓣置换,29例患者行瓣下肌切除术,13例患者行冠状动脉旁路移植术。该手术的住院死亡率较低(2%),术后发病率也较低。缩窄后计算机断层扫描和超声心动图测量的直径显著减小(CT:从55.8±9mm降至40.51±6.2mm,p<0.002;超声心动图:术前54.1±6.7mm降至38.7±7.1mm,p<0.002),长期随访中功能稳定(平均随访时间:70个月)。
如本研究所示,采用带外部加固的主动脉成形术缩小升主动脉大小是一种安全的手术方法,长期效果良好。对于主动脉瓣和主动脉根部的窦管交界未受损害的主动脉狭窄后扩张患者,这是现代主动脉手术中的一种治疗选择。