辅助放化疗后晚期胃肠道黏膜损伤的内镜评分
Endoscopic scoring of late gastrointestinal mucosal damage after adjuvant radiochemotherapy.
作者信息
Dabak Resat, Uygur-Bayramicli Oya, Gemici Cengiz, Yavuzer Dilek, Sargin Mehmet, Yildirim Mehmet
机构信息
Department of Family Medicine, Kartal State Hospital, Kartal, Istanbul, Turkey.
出版信息
World J Gastroenterol. 2006 Jul 21;12(27):4411-5. doi: 10.3748/wjg.v12.i27.4411.
AIM
To evaluate late effects of chemoradiation on gastrointestinal mucosa with an endoscopic scoring system and compare it to a clinical scoring system.
METHODS
Twenty-four patients going to receive chemoradiation after gastric surgery underwent endoscopy four wk after surgery and one year after the chemoradiation finished. Upper gastrointestinal findings were recorded according to a system proposed by World Organisation for Digestive Endoscopy (OMED) and clinical scoring was done with RTOG-EORTC radiation morbidity scoring systems.
RESULTS
There was no significant endoscopic difference in gastric and intestinal mucosa after chemoradiation (P > 0.05) and there was no association between endoscopic scores and clinical scores. Endoscopic changes were minimal.
CONCLUSION
Late effects after chemoradiation in operated patients with gastric cancers can be evaluated with an endoscopic scoring system objectively and this system is superior to clinical scoring systems.
目的
采用内镜评分系统评估放化疗对胃肠道黏膜的远期影响，并与临床评分系统进行比较。
方法
24例胃癌术后接受放化疗的患者在术后4周及放化疗结束1年后接受内镜检查。根据世界消化内镜组织（OMED）提出的系统记录上消化道检查结果，并使用RTOG-EORTC放射损伤评分系统进行临床评分。
结果
放化疗后胃和肠黏膜的内镜检查结果无显著差异（P>0.05），内镜评分与临床评分之间无相关性。内镜改变轻微。
结论
内镜评分系统可客观评估胃癌手术患者放化疗后的远期影响，且该系统优于临床评分系统。
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