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鼻泪管支架取出后的长期结果及影响通畅性的因素

Long-term results and factors affecting patency after removal of nasolacrimal stents.

作者信息

Kim Jin Hyoung, Shin Ji Hoon, Song Ho-Young, Kang Weechang, Lim Jin-Oh, Park Seong Ho, Ko Gi Young, Yoon Hyun-Ki, Sung Kyu Bo

机构信息

Department of Radiology, Armed Forces Byukjae Hospital, Goyang, Korea.

出版信息

J Vasc Interv Radiol. 2006 Jul;17(7):1125-30. doi: 10.1097/01.RVI.0000228340.31347.40.

Abstract

PURPOSE

To retrospectively evaluate the long-term patency and prognostic factors affecting patency after removal of nasolacrimal stents.

MATERIALS AND METHODS

Lacrimal polyurethane stents were removed from 317 lacrimal drainage systems of 275 patients because the stent ceased to function, and immediate and maintained patency were determined with follow-up dacryocystography (DCG) after stent removal. Prognostic factors for patency after stent removal were evaluated by univariate and multivariate analyses for immediate patency and Kaplan-Meier survival analysis and multivariate analysis for maintained patency.

RESULTS

All stents were successfully removed under fluoroscopic or endoscopic guidance. After stent removal, 243 lacrimal systems (77%) showed immediate patency. The size of the lacrimal sac was the same (65% of cases), widened (2%), or contracted (33%) after stent removal. The shape of the lacrimal sac was normal in 30% and irregular in 70% of cases after stent removal. Seven-day follow-up DCG was obtained in 169 cases, and maintained patency of the lacrimal system was confirmed on 7-day follow-up DCG in 125 cases. Epiphora recurred in 70 cases (56%) during the mean 8-month follow-up period (range, 1-48 months). The mean maintained patency period after stent removal was 15.7 +/- 2.1 months. The maintained patency rates were 41% at 1 year, 31% at 2 years, and 14% at 4 years after stent removal. Multivariate analysis showed that the size of the lacrimal sac (P < .001) was the only factor affecting immediate and maintained patency after stent removal.

CONCLUSIONS

After stent removal in patients with nasolacrimal stent obstruction, the immediate patency rate was 77%; however, the rate of maintained patency decreased progressively with time. The major factor negatively affecting immediate and maintained patency after stent removal was contraction of the lacrimal sac at the time of stent removal.

摘要

目的

回顾性评估鼻泪管支架取出术后的长期通畅情况及影响通畅的预后因素。

材料与方法

因支架失去功能,从275例患者的317个泪道系统中取出泪道聚氨酯支架,支架取出后通过随访泪囊造影(DCG)确定即刻通畅和持续通畅情况。通过单因素和多因素分析评估支架取出后通畅的预后因素,其中单因素和多因素分析用于评估即刻通畅情况,Kaplan-Meier生存分析和多因素分析用于评估持续通畅情况。

结果

所有支架均在透视或内镜引导下成功取出。支架取出后,243个泪道系统(77%)显示即刻通畅。支架取出后泪囊大小与术前相同(65%的病例)、增大(2%)或缩小(33%)。支架取出后,30%的病例泪囊形状正常,70%的病例不规则。169例患者进行了7天随访DCG,其中125例在7天随访DCG时确认泪道系统持续通畅。在平均8个月的随访期(范围1 - 48个月)内,70例(56%)患者出现溢泪复发。支架取出后平均持续通畅时间为15.7±2.1个月。支架取出后1年、2年和4年的持续通畅率分别为41%、31%和14%。多因素分析显示,泪囊大小(P <.001)是影响支架取出后即刻和持续通畅的唯一因素。

结论

鼻泪管支架阻塞患者支架取出后,即刻通畅率为77%;然而,持续通畅率随时间逐渐下降。支架取出后对即刻和持续通畅产生负面影响的主要因素是支架取出时泪囊缩小。

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