Fraysse Bernard, Macías Angel Ramos, Sterkers Olivier, Burdo Sandro, Ramsden Richard, Deguine Olivier, Klenzner Thomas, Lenarz Thomas, Rodriguez Manuel Manrique, Von Wallenberg Ernst, James Chris
Hôpital Purpan, Toulouse, France.
Otol Neurotol. 2006 Aug;27(5):624-33. doi: 10.1097/01.mao.0000226289.04048.0f.
To assess the conservation of residual hearing in recipients of the Nucleus 24 Contour Advance cochlear implant (CI) and the benefits of combined electrical and acoustic stimulation.
Prospective multicenter study.
CI clinics in Western Europe.
Adult candidates for conventional cochlear implantation with a minimum preoperative word recognition score of 10% in the ear to be implanted.
"Soft-surgery" protocol, including a 1- to 1.2-mm anterior and inferior cochleostomy hole with the electrode array, inserted 17 mm using the "advance-off-stylet" technique. Patients with postoperative pure-tone hearing threshold levels (HTLs) of 80 dB hearing loss or less at 125 and 250 Hz and 90 dB hearing loss or less at 500 Hz were refitted with an in-the-ear hearing aid for combined ipsilateral electrical and acoustic (El-Ac) stimulation.
A questionnaire to collect information regarding surgery. Pure-tone HTLs measured at intervals. Word recognition tested in quiet and sentence recognition tested in noise at 10 and 5 dB signal-to-noise ratio (SNR). HEARING CONSERVATION RESULTS: HTL data were available for 27 patients. HTLs were conserved within 20 dB of preoperative levels for 33, 26, and 19% of patients for 125, 250, and 500 Hz, respectively. However, the recommended soft-surgery protocol was strictly followed in only 12 of 27 patients. For these 12 patients, hearing thresholds were conserved within 20 dB for 50, 50, and 33% of patients. Median threshold increases were 40 dB (range, 250-500 Hz) for the whole group and 23 dB for the strict surgery group. Ten patients retained sufficient HTLs to enter the El-Ac user group. SPEECH RECOGNITION RESULTS: Group mean recognition scores for nine El-Ac users for words presented at 65 dB sound pressure level were 45% for CI alone and 55% for CI + ipsilateral hearing aid (p < 0.05, paired t). For sentences presented in noise at 5 dB SNR, mean word scores were 46% CI alone and 56% CI + ipsilateral hearing aid (p < 0.01, paired t).
Hearing was conserved for conventional candidates for cochlear implantation where the recommended soft-surgery protocol was strictly adhered. Combined ipsilateral electrical and acoustic stimulation provided considerable benefits for speech recognition in noise, equivalent to between 3 and 5 dB SNR, compared with CI alone.
评估接受Nucleus 24 Contour Advance人工耳蜗植入(CI)患者的残余听力保留情况以及电刺激和声刺激联合应用的益处。
前瞻性多中心研究。
西欧的人工耳蜗植入诊所。
拟接受传统人工耳蜗植入的成年人,拟植入耳术前单词识别得分最低为10%。
“软手术”方案,包括使用电极阵列制作1至1.2毫米的前下方耳蜗造瘘孔,采用“推进式针芯分离”技术将电极阵列插入17毫米。术后在125和250赫兹时纯音听力阈值水平(HTL)损失80分贝及以下、在500赫兹时损失90分贝及以下的患者,重新佩戴耳内式助听器以进行同侧电刺激和声刺激联合(电-声)刺激。
收集有关手术信息的问卷。定期测量纯音HTL。在安静环境中测试单词识别,在信噪比为10和5分贝的噪声环境中测试句子识别。
有27例患者的HTL数据可用。在125、250和500赫兹时,分别有33%、26%和19%的患者HTL保留在术前水平的20分贝以内。然而,27例患者中只有12例严格遵循了推荐的软手术方案。对于这12例患者,分别有50%、50%和33%的患者听力阈值保留在20分贝以内。整个组的阈值增加中位数为40分贝(范围为250 - 500赫兹),严格遵循手术方案组为23分贝。10例患者保留了足够的HTL以进入电-声联合刺激用户组。
9例电-声联合刺激用户在65分贝声压级下呈现单词时的组平均识别得分,仅人工耳蜗植入时为45%,人工耳蜗植入 + 同侧助听器时为55%(p < 0.05,配对t检验)。在信噪比为5分贝的噪声环境中呈现句子时,平均单词得分仅人工耳蜗植入时为46%,人工耳蜗植入 + 同侧助听器时为56%(p < 0.01,配对t检验)。
对于严格遵循推荐软手术方案的传统人工耳蜗植入候选者,听力得以保留。同侧电刺激和声刺激联合应用在噪声环境中的言语识别方面提供了显著益处,与仅人工耳蜗植入相比,相当于信噪比提高了3至5分贝。