Wainwright P E
Department of Health Studies, University of Waterloo, Ontario, Canada.
Nutrition. 1991 Nov-Dec;7(6):443-6.
There appear to be mechanisms that enable the developing brain to regulate its concentration of 22:6n-3 in response to both dietary deficiencies and excesses. This appears to be true whether the n-3 fatty acids are supplied as 18:3n-3 or the long-chain derivatives, suggesting that the presence of 22:6n-3 during development may be of functional consequence to the operation of the nervous system. Although there is experimental support for specific effects of n-3 fatty acids on retinal function, further studies with better methodological controls are needed before effects on cognitive function in rodents can be considered unequivocal.
似乎存在一些机制，使发育中的大脑能够根据饮食中的不足和过量来调节其22:6n-3的浓度。无论n-3脂肪酸是以18:3n-3还是长链衍生物的形式提供，情况似乎都是如此，这表明发育过程中22:6n-3的存在可能对神经系统的运作具有功能性影响。尽管有实验支持n-3脂肪酸对视网膜功能的特定作用，但在啮齿动物认知功能的影响被视为明确之前，还需要进行方法学控制更好的进一步研究。
