[莫斯科人群中低氧诱导因子-1α基因IVS9-675C>A多态性与急性缺血性卒中的关联]
[Association of the IVS9-675C > A polymorphism of the HIF-1alpha gene with acute ischemic stroke in the Moscow population].
作者信息
Tupitsyna T V, Slominskiĭ P A, Shadrina M I, Shetova I M, Skvortsova V I, Limborskaia S A
出版信息
Genetika. 2006 Jun;42(6):858-61.
PMID:16871792
Abstract
The IVS9-675C > A polymorphism of the HIF-1alpha gene was analyzed in patients with acute ischemic stroke and in a control group. The genotype and allele frequencies proved to significantly differ between the two groups. Allele C and genotypes containing this allele were associated with a higher risk of stroke in the Moscow population.
摘要
在急性缺血性中风患者和对照组中分析了低氧诱导因子-1α（HIF-1α）基因的IVS9-675C>A多态性。结果证明，两组之间的基因型和等位基因频率存在显著差异。在莫斯科人群中，等位基因C和含有该等位基因的基因型与中风风险较高相关。
Zotero 插件