从交让木中分离得到的生物碱——交让木碱A-C

Daphnioldhanins A-C, alkaloids from Daphniphyllum oldhami.

作者信息

Mu Shu-Zhen, Wang Ye, He Hong-Ping, Yang Xian-Wen, Wang Yue-Hu, Di Ying-Tong, Lu Yang, Chang Ying, Hao Xiao-Jiang

机构信息

Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, People's Republic of China.

出版信息

J Nat Prod. 2006 Jul;69(7):1065-9. doi: 10.1021/np060131z.

DOI:10.1021/np060131z

PMID:16872145

Abstract

Three new Daphniphyllum alkaloids, daphnioldhanins A-C (1-3), along with four known ones, were isolated from the aerial parts of saplings of Daphniphyllum oldhami. The structures of these alkaloids were established by spectroscopic methods. The relative configuration of 1 was further confirmed by a single-crystal X-ray diffraction analysis. In addition, the (1)H and (13)C NMR data of the free base of daphmanidin A (4) were compared with its hydrochloric salt form.

摘要

从交让木幼树的地上部分分离得到了3个新的交让木生物碱——交让醇丹宁A-C（1-3）以及4个已知生物碱。通过光谱方法确定了这些生物碱的结构。通过单晶X射线衍射分析进一步确定了1的相对构型。此外，还比较了交让木定A（4）游离碱及其盐酸盐形式的氢核磁共振（¹H）和碳核磁共振（¹³C）数据。