长序虎皮楠中的虎皮楠属植物及二萜生物碱

Daphniphyllum and diterpenoid alkaloids from Daphniphyllum longeracemosum.

作者信息

Li Chun-Shun, Di Ying-Tong, Mu Shu-Zhen, He Hong-Ping, Zhang Qiang, Fang Xin, Zhang Yu, Li Shun-Lin, Lu Yang, Gong Yan-Qing, Hao Xiao-Jiang

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.

出版信息

J Nat Prod. 2008 Jul;71(7):1202-6. doi: 10.1021/np8001332. Epub 2008 Jun 14.

DOI:10.1021/np8001332

PMID:18553922

Abstract

Four new Daphniphyllum alkaloids, daphlongamines A-D (1-4), were isolated from the fruits of Daphniphyllum longeracemosum. Their structures were characterized by spectroscopic methods, especially 2D NMR techniques. A single-crystal X-ray diffraction analysis was used to confirm the stereochemistry of 3. Remarkably, this is the first report of aconitine- and veatchine-type diterpenoid alkaloids from the genus Daphniphyllum.

摘要

从长序虎皮楠的果实中分离出了四种新的虎皮楠生物碱，即长序虎皮楠胺A-D（1-4）。通过光谱方法，尤其是二维核磁共振技术对它们的结构进行了表征。采用单晶X射线衍射分析确定了3的立体化学结构。值得注意的是，这是首次从虎皮楠属植物中报道乌头碱型和藜芦碱型二萜生物碱。