Faubion William A, Bousvaros Athos
Division of Pediatric Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Clin Gastroenterol Hepatol. 2006 Oct;4(10):1199-213. doi: 10.1016/j.cgh.2006.05.031. Epub 2006 Jul 26.
Crohn's disease is a common indication for referral to pediatric gastroenterology. While most patients with Crohn's disease respond to standard induction therapy, steroid-refractory or steroid-dependent disease is a frequently encountered problem. This review discusses the data existing in both the adult and pediatric literature for medical therapy of refractory pediatric Crohn's disease.
克罗恩病是转诊至儿科胃肠病学的常见指征。虽然大多数克罗恩病患者对标准诱导疗法有反应,但激素难治性或激素依赖性疾病是一个经常遇到的问题。本综述讨论了成人和儿科文献中关于难治性儿科克罗恩病药物治疗的现有数据。