Mollison Heather L, McKay William P S, Patel Rajesh H, Kriegler Stefan, Negraeff October E
Department of Anesthesia, University of Saskatchewan, Saskatoon, Canada.
Can J Anaesth. 2006 Aug;53(8):759-63. doi: 10.1007/BF03022791.
To determine the effect of reactive hyperemia on human forearm vein area.
After obtaining ethics approval and informed consent, an automatic tourniquet was applied to the forearms of 20 healthy subjects for one, two, and three minutes, at pressures of 25 mmHg, 200 mmHg, then 25 mmHg. A blinded radiographer measured the cross-sectional area of the cephalic vein at the wrist using ultrasonography. Measurements were recorded prior to tourniquet application and every minute thereafter for ten minutes, at each pressure setting and each time interval.
The mean vein cross-sectional area (mm2) increased from 8.22 +/- 3.09 to 10.77 +/- 3.50 after one minute of ischemia, from 8.31 +/- 2.78 to 10.61 +/- 2.77 after two minutes of ischemia, and from 8.39 +/- 3.34 to 10.94 +/- 3.46 after three minutes of ischemia (P < 0.05 for all). A tourniquet inflated to 25 mmHg for 13 min produced a mean vein cross-sectional area of 10.71 +/- 3.25 mm2.
Reactive hyperemia causes human forearm vein cross-sectional area to increase. A low pressure tourniquet will also increase forearm vein area, but veins dilate more quickly during reactive hyperemia. This may have important clinical implications for attempting venous cannulation in patients with difficult venous access.
确定反应性充血对人前臂静脉面积的影响。
在获得伦理批准并取得知情同意后,对20名健康受试者的前臂使用自动止血带,分别施加25 mmHg、200 mmHg、然后25 mmHg的压力,持续1分钟、2分钟和3分钟。一名不知情的放射技师使用超声测量手腕处头静脉的横截面积。在施加止血带之前以及之后的每个压力设置和每个时间间隔,每分钟记录一次测量值,共记录10分钟。
缺血1分钟后,平均静脉横截面积(mm²)从8.22±3.09增加到10.77±3.50;缺血2分钟后,从8.31±2.78增加到10.61±2.77;缺血3分钟后,从8.39±3.34增加到10.94±3.46(所有P<0.05)。充气至25 mmHg持续13分钟的止血带产生的平均静脉横截面积为10.71±3.25 mm²。
反应性充血导致人前臂静脉横截面积增加。低压止血带也会增加前臂静脉面积,但在反应性充血期间静脉扩张更快。这对于试图对静脉穿刺困难的患者进行静脉置管可能具有重要的临床意义。