Nakamura J, Otsuka M, Kuniyoshi M, Inanaga K
Department of Neuropsychiatry, Kurume University School of Medicine, Japan.
Jpn J Psychiatry Neurol. 1991 Dec;45(4):833-41. doi: 10.1111/j.1440-1819.1991.tb00522.x.
We present here three cases of respiratory dyskinesia (RD). RD was observed with a video recording and other recordings were made of a respiratory airflow with a thermistor, and abdominal movement with a strain gauge. Neurological findings and CT scanning indicated marked organic changes in the brain in these 3 cases. RD was complicated with tardive dyskinesia of the tongue and lips, and the symptoms were aggravated during stress and absent during sleeping, which are the characteristic features of extrapyramidal symptoms. The symptoms of the three cases have improved by decreasing the dose of butyrophenone derivatives and discontinuing anti-parkinsonian drugs, which suggested that an intracerebral imbalance of DA and ACh may be the cause of RD.
我们在此呈现三例呼吸运动障碍（RD）。通过视频记录观察到RD，并用热敏电阻记录呼吸气流，用应变仪记录腹部运动。神经学检查结果和CT扫描显示这3例患者脑部有明显器质性改变。RD合并有舌和唇部的迟发性运动障碍，症状在应激时加重，睡眠时消失，这是锥体外系症状的特征。通过减少丁酰苯衍生物剂量和停用抗帕金森病药物，这三例患者的症状有所改善，提示脑内多巴胺（DA）和乙酰胆碱（ACh）失衡可能是RD的病因。
