Wright C V
Vanderbilt University, Nashville, Tennessee.
Curr Opin Cell Biol. 1991 Dec;3(6):976-82. doi: 10.1016/0955-0674(91)90116-g.
Recent highlights in vertebrate homeobox gene research include the discovery of new genes with novel expression patterns, observations that peptide growth factors and retinoic acid influence homeobox gene expression, and the generation of mutant phenotypes of embryos homozygous for null mutations. These combined studies reinforce the idea that homeobox genes function near the top of the gene hierarchies controlling vertebrate embryogenesis.
脊椎动物同源框基因研究的近期亮点包括发现具有新表达模式的新基因、观察到肽生长因子和视黄酸影响同源框基因表达，以及产生纯合无效突变胚胎的突变表型。这些综合研究强化了同源框基因在控制脊椎动物胚胎发育的基因层级中处于顶端发挥作用的观点。
