Tancioni Flavio, Di Ieva Antonio, Levi Daniel, Aimar Enrico, Debernardi Alberto, Colombo Piergiuseppe, Gaetani Paolo, Rodriguez Y Baena Riccardo
Department of Neurosurgery, Istituto Clinico HUMANITAS, 20089 Milan, Italy.
Surg Neurol. 2006 Aug;66(2):189-91; discussion 191. doi: 10.1016/j.surneu.2005.11.058.
Paget's disease is an osteometabolic disorder affecting in particular long bones. The spine is the second most commonly involved site in Paget's disease. This pathology can cause low back pain, spinal stenosis, myeloradiculopathy, and vertebral collapse. Medical therapy is the first choice for the treatment of Paget's disease of the spine; in case of failure, surgery remains a valid option. In the present article, we report a case of a patient with leg disability due to myelopathy caused by spinal Paget's disease treated with spinal decompression and vertebroplasty. To our knowledge, this is the first case report in which these procedures have been performed together in the same operation to treat spinal pathologies due to Paget's disease.
佩吉特病是一种骨代谢紊乱疾病,尤其影响长骨。脊柱是佩吉特病第二常见的受累部位。这种病理情况可导致腰痛、椎管狭窄、脊髓神经根病和椎体塌陷。药物治疗是脊柱佩吉特病治疗的首选;若治疗失败,手术仍是一种有效的选择。在本文中,我们报告了一例因脊柱佩吉特病导致脊髓病而出现腿部残疾的患者,该患者接受了脊柱减压和椎体成形术治疗。据我们所知,这是首例在同一手术中同时进行这些操作以治疗佩吉特病所致脊柱病变的病例报告。