Kayama Y, Ito S, Koyama Y, Jodo E
Department of Physiology, Fukushima Medical College, Japan.
Fukushima J Med Sci. 1991 Dec;37(2):59-74.
The classical concept of the ascending reticular activating system was reviewed basing upon recent neuroanatomical findings and two kinds of physiological studies, such as recording from brainstem neurons in the discrete nuclei and stimulation of the brainstem nuclei influencing thalamic neuronal activity. We propose that the reticular activating system is not a single system, but is composed of two systems arising from the brainstem: the noradrenergic projection conveying a rather tonic control, and the cholinergic projection responsible for the phasic aspects of the activating system.
基于最近的神经解剖学发现以及两类生理学研究，如对离散核团中脑干神经元的记录和对影响丘脑神经元活动的脑干核团的刺激，对上行网状激活系统的经典概念进行了综述。我们提出，网状激活系统并非单一系统，而是由源自脑干的两个系统组成：去甲肾上腺素能投射传递一种较为持续性的控制，胆碱能投射则负责激活系统的相位性方面。
