Son Ho Sung, Sun Kyung, Hwang Chang Mo, Fang Yong Hu, Lim Choon Hak, Lee Hye Won, Park Sung Min, Shin Jae Seung, Kim Kwang Taik, Kim Hyoung Mook
Department of Thoracic and Cardiovascular Surgery, Korea University, Seoul, Korea.
ASAIO J. 2006 Jul-Aug;52(4):386-90. doi: 10.1097/01.mat.0000227692.75032.86.
Most patients needing implantation of a ventricular assist device (VAD) require repeated sternotomy; some after cardiac surgery, and others later for heart transplantation. The purpose of this study was to establish the right thoracotomy technique as an alternative for VAD implantation to reduce repeated sternotomy-related morbidity and mortality. We performed a right thoracotomy in animals, preclinical cadaver fitting tests, and a clinical case. A total of 20 various animals underwent right thoracotomy for implantation of bi-VAD (BVAD, n = 17) and left VAD (LVAD, n = 3). The right chest cavity was entered through the fourth intercostal space with partial resection of the fifth rib. There was no procedure-related morbidity or mortality, except for one calf with right anterior leg paralysis. Preclinical fitting tests were performed on 7 human cadavers to observe the anatomical feasibility of BVAD cannulation from the right side of the heart. In humans, the ascending aorta, interatrial groove, right atrium, and main pulmonary artery were identified as optimal cannula insertion sites for BVAD implantation. A patient with cardiogenic shock underwent a right thoracotomy for implantation of an external LVAD. Cardiac function recovered after 3 weeks, and the device was successfully explanted through a repeat right thoracotomy. In conclusion, a right thoracotomy can be an alternative method to the standard median sternotomy for patients who need repeated sternotomy because of previous cardiac surgery, transplantation at a later date, or those with mediastinal infections.
大多数需要植入心室辅助装置(VAD)的患者需要多次开胸手术;一些是在心脏手术后,另一些则是后来进行心脏移植时。本研究的目的是确立右胸切开术技术作为VAD植入的一种替代方法,以降低与多次开胸手术相关的发病率和死亡率。我们在动物身上进行了右胸切开术、临床前尸体适配测试以及一个临床病例。共有20只不同的动物接受了右胸切开术以植入双心室辅助装置(BVAD,n = 17)和左心室辅助装置(LVAD,n = 3)。通过第四肋间间隙进入右胸腔,并部分切除第五肋骨。除了一只出现右前腿麻痹的小牛外,没有与手术相关的发病率或死亡率。对7具人类尸体进行了临床前适配测试,以观察从心脏右侧插入BVAD插管的解剖学可行性。在人类中,升主动脉、房间沟、右心房和主肺动脉被确定为BVAD植入的最佳插管插入部位。一名心源性休克患者接受了右胸切开术以植入外置LVAD。3周后心脏功能恢复,并且通过再次右胸切开术成功取出了该装置。总之,对于因既往心脏手术、日后移植或患有纵隔感染而需要多次开胸手术的患者,右胸切开术可以作为标准正中开胸术的一种替代方法。