Lee Richard, Hutnik Cindy M L
Faculty of Medicine and Dentistry, University of Western Ontario, London, Ont., Canada.
Can J Ophthalmol. 2006 Aug;41(4):449-56. doi: 10.1016/S0008-4182(06)80006-2.
The projected 6-year cost comparison of primary selective laser trabeculoplasty (SLT) versus primary medical therapy in the treatment of open-angle glaucoma for Ontario patients aged 65 years or more is presented. Costs are taken from the perspective of the Ontario Health Insurance Plan at a per-patient level.
The cost of each medication was obtained from the 2003 Ontario Drug Benefits formulary. The average annual cost of medications was determined by estimating the provincial prescription rate of glaucoma medications, with reference to both a volume-per-bottle study of these drugs and a study of pharmacy claims reports. A representative provincial prescription rate was calculated by reviewing 707 patient charts selected randomly from 5 ophthalmologic practices across Ontario. Medication therapies were categorized into mono-, bi-, and tri-drug therapy groups. The cost of SLT was analyzed under the following 2 scenarios. SLT rep 2y assumed a duration of 2 years before repeat SLT was necessary. SLT rep 3y assumed a duration of 3 years before repeat SLT was necessary. Bilateral 180 degrees SLT treatment and repeatability of SLT was assumed. The cost of surgery for patients who fail SLT or medical therapy was not accounted for in this study nor was the cost of patients who required medical therapy in conjunction with SLT.
In the SLT rep 2y scenario, the use of primary SLT over mono-, bi-, and tri-drug therapy produced a 6-year cumulative cost savings of 206.54 dollars, 1668.64 dollars, and 2992.67 dollars per patient, respectively. In the SLT rep 3y scenario, the use of primary SLT over mono-, bi-, and tri-drug therapy produced a 6-year cumulative cost savings of 580.52 dollars, 2042.82 dollars, and 3366.65 dollars per patient, respectively.
Our findings suggest that SLT as primary therapy, at a per-patient level, offers a modest potential cost saving over primary medical therapy in the management of open-angle glaucoma for Ontario patients aged 65 years or more.
本文呈现了安大略省65岁及以上患者原发性开角型青光眼采用选择性激光小梁成形术(SLT)与原发性药物治疗的6年成本比较。成本是从安大略省医疗保险计划的角度,按每位患者计算得出。
每种药物的成本取自2003年安大略省药物福利处方集。通过参考这些药物的每瓶用量研究和药房索赔报告研究,估算青光眼药物的省级处方率,从而确定药物的年均成本。通过审查从安大略省5家眼科诊所随机抽取的707份患者病历,计算出具有代表性的省级处方率。药物治疗分为单药、双药和三药治疗组。在以下两种情况下分析SLT的成本。SLT重复治疗2年的情况假设在需要重复SLT之前持续2年。SLT重复治疗3年的情况假设在需要重复SLT之前持续3年。假设进行双侧180度SLT治疗且SLT具有可重复性。本研究未考虑SLT或药物治疗失败患者的手术成本,也未考虑需要SLT联合药物治疗患者的成本。
在SLT重复治疗2年的情况下,与单药、双药和三药治疗相比,采用原发性SLT治疗每位患者6年累计成本分别节省206.54美元、1668.64美元和2992.67美元。在SLT重复治疗3年的情况下,与单药、双药和三药治疗相比,采用原发性SLT治疗每位患者6年累计成本分别节省580.52美元、2042.82美元和3366.65美元。
我们的研究结果表明,对于安大略省65岁及以上的开角型青光眼患者,在每位患者层面,SLT作为主要治疗方法相较于原发性药物治疗可能会节省一定成本。