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选择性激光小梁成形术治疗 25 岁以下青少年开角型青光眼。

Selective laser trabeculoplasty in the treatment of juvenile open angle glaucoma patients under 25 years of age.

机构信息

Sistem Eye Hospital, Istanbul, Turkey.

出版信息

Int Ophthalmol. 2024 Apr 26;44(1):201. doi: 10.1007/s10792-024-03108-7.

Abstract

AIM

To retrospectively evaluate the effectiveness and reliability of selective laser trabeculoplasty (SLT) treatment in juvenile open angle glaucoma (JOAG) cases.

MATERIAL AND METHOD

The 46 eyes of 28 cases that had undergone SLT for JOAG and had a follow-up of at least one month were included in the study. The pre-SLT, month 1, month 6, year 1, year 2, and final follow-up intraocular pressure (IOP); the number of drugs before and after the SLT procedure; and the complications caused by the SLT were recorded. An IOP below 21 mmHg without any additional medication or glaucoma surgery and an IOP decrease of 20% or more compared to the baseline were considered successful.

RESULTS

There were 18 females and 10 males with a mean age of 17.52 ± 2.7 (13-22) years. The cases were followed-up for a mean duration of 39 (5-59) months. The mean IOP was 23.93 ± 0.52 mmHg before SLT and decreased to 17.15 ± 0.57 mmHg at month 1 after the procedure, 17.17 ± 0.52 mmHg at month 6, 18.02 ± 0.77 mmHg at year 1, 18.12 ± 0.48 mmHg at year 2, and 20.93 ± 0.69 mmHg at the final follow-up. The post-SLT IOP measurements at all times were found to be significantly lower than the pre-SLT values (p < 0.001). The mean number of drugs was 1.5 before the SLT and 0.59 afterwards (p < 0.001). The most common complications after SLT were anterior chamber inflammation in 29 cases (63.04%), hyperemia in 20 (43.40%) cases (4.34%), an early period IOP increase of 5 mmHg or more in 11 cases (23.91%), and mild ocular pain in 2 cases (4.34%).

CONCLUSION

SLT is an effective and reliable method for JOAG treatment.

摘要

目的

回顾性评估选择性激光小梁成形术(SLT)治疗青少年开角型青光眼(JOAG)的疗效和可靠性。

材料和方法

本研究纳入了 28 例 46 眼接受 SLT 治疗的 JOAG 患者,随访时间至少 1 个月。记录 SLT 前、术后 1 个月、术后 6 个月、术后 1 年、术后 2 年及最终随访时的眼压(IOP);SLT 前后的药物使用数量;以及 SLT 引起的并发症。无其他药物或青光眼手术治疗且 IOP 低于 21mmHg,或与基线相比 IOP 下降 20%或更多被认为是成功的。

结果

患者中女性 18 例,男性 10 例,平均年龄 17.52±2.7(13-22)岁。平均随访时间为 39(5-59)个月。SLT 前平均 IOP 为 23.93±0.52mmHg,术后 1 个月时降至 17.15±0.57mmHg,术后 6 个月时为 17.17±0.52mmHg,术后 1 年时为 18.02±0.77mmHg,术后 2 年时为 18.12±0.48mmHg,最终随访时为 20.93±0.69mmHg。所有时间点的 SLT 后 IOP 测量值均显著低于 SLT 前(p<0.001)。SLT 前平均用药数量为 1.5 种,SLT 后为 0.59 种(p<0.001)。SLT 后最常见的并发症是前房炎症 29 例(63.04%)、充血 20 例(43.40%)(4.34%)、早期眼压升高 5mmHg 或以上 11 例(23.91%)和轻度眼痛 2 例(4.34%)。

结论

SLT 是治疗 JOAG 的有效且可靠的方法。

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