Rodrigues George, Yartsev Slav, Chen Jeff, Wong Eugene, D'Souza David, Lock Michael, Bauman Glenn, Grigorov Grigor, Kron Tomas
Department of Radiation Oncology, London Health Sciences, London, Ont., Canada.
Radiother Oncol. 2006 Sep;80(3):374-7. doi: 10.1016/j.radonc.2006.07.005. Epub 2006 Aug 1.
The purpose of this study was to assess a variety of potential IMRT class solutions as compared to a helical tomotherapy (HT) class solution for localized prostate cancer. Target and critical structures were contoured on 10 prostate cancer patient CT datasets. HT treatment plans were compared to four different IMRT approaches by paired t-tests. HT prostate planning generally provided treatment plans with excellent target homogeneity and favorable critical structure sparing when compared to conventional IMRT.
本研究的目的是评估多种潜在的调强放射治疗(IMRT)类解决方案,并与螺旋断层放射治疗(HT)类解决方案用于局部前列腺癌时的情况进行比较。在10个前列腺癌患者的CT数据集中勾勒出靶区和关键结构。通过配对t检验将HT治疗计划与四种不同的IMRT方法进行比较。与传统IMRT相比,HT前列腺计划通常能提供具有出色靶区均匀性且对关键结构保护良好的治疗计划。