Department of Medical Physics, British Columbia Cancer Agency, Victoria, British Columbia, Canada.
J Appl Clin Med Phys. 2009 Oct 7;10(4):117-131. doi: 10.1120/jacmp.v10i4.3068.
The purpose of this study is to examine plan quality, treatment planning time, and estimated treatment delivery time for 5- and 9-field sliding window IMRT, single and dual arc RapidArc, and tomotherapy. For four phantoms, 5- and 9-field IMRT, single and dual arc RapidArc and tomotherapy plans were created. Plans were evaluated based on the ability to meet dose-volume constraints, dose homogeneity index, radiation conformity index, planning time, estimated delivery time, integral dose, and volume receiving more than 2 and 5 Gy. For all of the phantoms, tomotherapy was able to meet the most optimization criteria during planning (50% for P1, 67% for P2, 0% for P3, and 50% for P4). RapidArc met less of the optimization criteria (25% for P1, 17% for P2, 0% for P3, and 0% for P4), while IMRT was never able to meet any of the constraints. In addition, tomotherapy plans were able to produce the most homogeneous dose. Tomotherapy plans had longer planning time, longer estimated treatment times, lower conformity index, and higher integral dose. Tomotherapy plans can produce plans of higher quality and have the capability to conform dose distributions better than IMRT or RapidArc in the axial plane, but exhibit increased dose superior and inferior to the target volume. RapidArc, however, is capable of producing better plans than IMRT for the test cases examined in this study.
本研究旨在考察 5 野和 9 野滑动窗口调强放疗（IMRT）、单弧和双弧 RapidArc 及螺旋断层放疗（Tomotherapy）的计划质量、治疗计划时间和预计治疗交付时间。针对四个体模，我们创建了 5 野和 9 野 IMRT、单弧和双弧 RapidArc 以及 Tomotherapy 计划。我们根据满足剂量-体积限制、剂量均匀性指数、辐射适形指数、计划时间、预计交付时间、积分剂量以及接收超过 2Gy 和 5Gy 的体积的能力来评估这些计划。对于所有体模，Tomotherapy 在计划中能够满足最多的优化标准（P1 为 50%，P2 为 67%，P3 为 0%，P4 为 50%）。RapidArc 满足的优化标准较少（P1 为 25%，P2 为 17%，P3 为 0%，P4 为 0%），而 IMRT 则从未能够满足任何约束条件。此外，Tomotherapy 计划能够产生更均匀的剂量。Tomotherapy 计划的计划时间更长，预计治疗时间更长，适形指数更低，积分剂量更高。Tomotherapy 计划能够生成质量更高的计划，并且在轴平面上具有更好地符合剂量分布的能力，优于 IMRT 或 RapidArc，但在靶区上下会出现剂量增加。然而，在本研究中检查的案例中，RapidArc 能够生成比 IMRT 更好的计划。
