Viguier Jérôme, De Muret Anne, Bacq Yannick
Service d'Hépatogastroentérologie, Hôpital Trousseau, Tours.
Gastroenterol Clin Biol. 2006 Jun-Jul;30(6-7):903-5. doi: 10.1016/s0399-8320(06)73340-1.
Ascites in patients with breast cancer is uncommon. We report the case of a 70-year-old woman with breast cancer and ascites caused by portal hypertension due to metastatic liver infiltration. There was no evidence of peritoneal carcinomatosis and the prothrombin index was normal. Portal hypertension was confirmed by increased hepatic venous pressure gradient. Histological examination of a liver biopsy obtained by the transjugular route demonstrated infiltration by malignant cells from the breast tumor. This case shows that, infiltration of the liver by metastases from breast cancer may lead to ascites due to portal hypertension, even in the absence of hepatic failure.
乳腺癌患者出现腹水的情况并不常见。我们报告了一例70岁患有乳腺癌的女性病例，其腹水是由转移性肝浸润导致的门静脉高压引起的。没有腹膜癌转移的证据，凝血酶原指数正常。通过增加肝静脉压力梯度证实了门静脉高压。经颈静脉途径获取的肝脏活检组织学检查显示有来自乳腺肿瘤的恶性细胞浸润。该病例表明，即使在没有肝功能衰竭的情况下，乳腺癌转移灶对肝脏的浸润也可能导致因门静脉高压引起的腹水。
