Rihal Charanjit S, Kamath Celia C, Holmes David R, Reller M Katherine, Anderson Stephanie S, McMurtry Erin K, Long Kirsten Hall
Cardiac Catheterization Laboratory, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Am J Manag Care. 2006 Aug;12(8):445-52.
To compare clinical and economic outcomes associated with percutaneous coronary intervention (PCI) in cohorts before and after continuous quality improvement (CQI) was instituted.
Observational study.
Clinical, angiographic, procedural, and outcome data on 1441 pre-CQI and 1760 post-CQI PCIs (performed in 1997 and 1998, respectively) were derived from an institutional PCI registry. Administrative data were used to estimate total procedural and postprocedural costs and length of stay (LOS). Logistic and generalized linear modeling was used to adjust in-hospital clinical and economic outcomes, respectively, for differences in patient characteristics.
The 2 cohorts were similar in terms of age, sex, and rate of diabetes. Post-CQI patients more often received intracoronary stents, had urgent PCIs, had a history of prior PCI, and received glycoprotein IIb/IIIa inhibitors. Procedural success without in-hospital complications occurred in 90% of both cohorts and did not differ statistically in adjusted analyses. Compared with patients treated pre-CQI, those treated post-CQI had a reduced adjusted odds ratio for in-hospital death or any myocardial infarction (odds ratio = 0.66; 95% confidence interval = 0.46, 0.95). Models predicted a mean postprocedural LOS difference of 0.8 days (2.8 days pre-CQI vs 2.0 days post-CQI; P <.001) and an average post-CQI cost savings of $5430 (P <.001).
Physician-led, multidisciplinary practice management efforts were successful at significantly reducing PCI-related costs in an era of rapid technological advances while maintaining and perhaps improving quality of care.
比较在实施持续质量改进(CQI)前后队列中经皮冠状动脉介入治疗(PCI)的临床和经济结果。
观察性研究。
1997年和1998年分别进行的1441例CQI前PCI和1760例CQI后PCI的临床、血管造影、手术及结果数据来自机构PCI登记处。行政数据用于估计总手术及术后成本和住院时间(LOS)。分别采用逻辑回归和广义线性模型对患者特征差异调整住院临床和经济结果。
两组在年龄、性别和糖尿病发生率方面相似。CQI后患者更常接受冠状动脉内支架置入、进行急诊PCI、有既往PCI史并接受糖蛋白IIb/IIIa抑制剂治疗。两组中90%的患者手术成功且无住院并发症,在调整分析中无统计学差异。与CQI前治疗的患者相比,CQI后治疗的患者住院死亡或任何心肌梗死的调整优势比降低(优势比 =
0.66;95%置信区间 = 0.46, 0.95)。模型预测术后平均住院时间差异为0.8天(CQI前2.8天 vs CQI后2.0天;P <.001),CQI后平均成本节省5430美元(P <.001)。
在技术快速发展的时代,由医生主导的多学科实践管理努力在显著降低PCI相关成本的同时,维持甚至可能提高了医疗质量。