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接受性腺毒性化疗的癌症青年男性精子库保存的促进因素和障碍:幸存者及医护人员的观点

Facilitators and obstacles to sperm banking in young men receiving gonadotoxic chemotherapy for cancer: the perspective of survivors and health care professionals.

作者信息

Achille Marie A, Rosberger Zeev, Robitaille Roxane, Lebel Sophie, Gouin Jean-Philippe, Bultz Barry D, Chan Peter T K

机构信息

Department of Psychology, Université de Montréal, Montreal, Quebec, Canada.

出版信息

Hum Reprod. 2006 Dec;21(12):3206-16. doi: 10.1093/humrep/del307. Epub 2006 Aug 3.

Abstract

BACKGROUND

Testicular cancer and Hodgkin's disease are among the most common malignancies to affect young men of reproductive age. Although both are associated with high rates of infertility, sperm banking (SB) remains underutilized by both diagnostic groups. Reasons for this remain elusive.

METHODS

This study used a qualitative design. In-depth interviews were conducted with 20 cancer survivors and 18 health care professionals (HCPs) to examine their perspectives on factors that facilitate or hinder SB. Interview data were analysed using a mixed approach and a three-step process of data reduction, data display and conclusion drawing and verification.

RESULTS

Eight factors were identified as having an impact on SB, and findings suggest that effective promotion of SB involves adequate communication around the severity and personal risk for infertility, assessing the importance of patients place on having children, emphasizing the benefits of SB and addressing possible obstacles such as cost, misperceptions or cultural and other factors. In addition, the communicator should be perceived as appealing.

CONCLUSIONS

These results are conceptually consistent with both the Health Belief Model and the Elaboration Likelihood Model of health promotion and are useful in informing HCPs on how to better promote SB.

摘要

背景

睾丸癌和霍奇金淋巴瘤是影响育龄期年轻男性的最常见恶性肿瘤。虽然这两种疾病都与高不孕率相关,但精子库(SB)在这两个诊断群体中仍未得到充分利用。其原因尚不清楚。

方法

本研究采用定性设计。对20名癌症幸存者和18名医疗保健专业人员(HCPs)进行了深入访谈,以考察他们对促进或阻碍精子库利用的因素的看法。访谈数据采用混合方法进行分析,并通过数据简化、数据展示以及得出结论和验证的三步过程进行分析。

结果

确定了八个对精子库利用有影响的因素,研究结果表明,有效推广精子库利用涉及围绕不孕的严重性和个人风险进行充分沟通,评估患者对生育的重视程度,强调精子库利用的益处,并解决可能的障碍,如成本、误解或文化及其他因素。此外,沟通者应被认为具有吸引力。

结论

这些结果在概念上与健康信念模型和健康促进的精细可能性模型一致,有助于告知医疗保健专业人员如何更好地推广精子库利用。

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