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伴有肝外恶性肿瘤的肝细胞癌

[Hepatocellular carcinoma with extrahepatic malignancies].

作者信息

Yoshikawa K, Mikata S, Inoue M, Amemiya A, Iwasaki T, Moriguchi S, Emoto T, Han N, Itou A

机构信息

Dept. of Surgery, Osaka Rosai Hospital.

出版信息

Gan No Rinsho. 1990 Jan;36(1):23-8.

PMID:1688958
Abstract

A clinical investigation of 16 hepatocellular carcinoma (HCC) patients with extrahepatic malignancies (13 male, 3 female) has been conducted. The age of these patients ranged from 55 to 76 years. Three of these double cancer cases were hemocronous, and 13 were heterochronous. The duration between the occurrence of the cancers ranged from 2 years and 4 months to 22 years. As for the site of the other cancer, the stomach was the most common organ (12 cases). In nine cases out of 16, the HCC was resected, whereas the other cases were treated with a TAE and hepatic artery ligation because the cancer were far advanced stages. Early detection of an HCC by AFP or an ultrasonographic examination, and a subsequent surgical resection in cases of a postoperative cancer patient with a liver dysfunction may lead to a more favorable prognosis.

摘要

对16例合并肝外恶性肿瘤的肝细胞癌(HCC)患者(13例男性,3例女性)进行了临床研究。这些患者的年龄在55至76岁之间。其中3例双癌病例为同时性,13例为异时性。两种癌症发生之间的时间间隔为2年4个月至22年。至于另一种癌症的部位,胃是最常见的器官(12例)。16例中有9例HCC进行了切除,而其他病例因癌症处于晚期而接受了经动脉栓塞化疗(TAE)和肝动脉结扎治疗。通过甲胎蛋白(AFP)或超声检查早期发现HCC,以及对肝功能不全的术后癌症患者进行后续手术切除可能会带来更有利的预后。

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