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哮喘患者中抑郁和焦虑与医疗保健利用及生活质量的关联。

Association of depression and anxiety with health care use and quality of life in asthma patients.

作者信息

Kullowatz Antje, Kanniess Frank, Dahme Bernhard, Magnussen Helgo, Ritz Thomas

机构信息

Department of Psychology, Southern Methodist University, Dallas, TX 75205, USA.

出版信息

Respir Med. 2007 Mar;101(3):638-44. doi: 10.1016/j.rmed.2006.06.002. Epub 2006 Aug 7.

Abstract

INTRODUCTION

Demographic factors, symptom severity, and psychopathology, in particular anxiety and depression, are known to influence health care use and quality of life in asthma. Because depression and anxiety are typically correlated, we sought to explore whether depression specifically is associated with health care utilization and quality of life when effects of anxiety are controlled for.

METHOD

In a cross-sectional questionnaire study, 88 asthma patients (46 women; age range 27-70 years) reported on symptoms and treatment of their disease, as well as anxiety and depression (Hospital Anxiety and Depression Scale, HADS), general quality of life (Short Form 12 Health Survey Questionnaire, SF-12) and asthmatic-specific quality of life (Living with Asthma, LAQ).

RESULTS

While no considerable associations between anxiety and health care use were found, the associations between higher scores in depression and hospital visits as well as days of corticosteroid intake were significant. Furthermore, considerable variance in all subscales of quality of life questionnaires was explained by higher scores in depression, even when controlling for anxiety. For anxiety scores these associations were comparable, except for physical well-being.

CONCLUSION

Depression is an important issue in asthma, as it is substantially related to quality of life and intake of corticosteroids, and marginally to hospitalization. Routine screening for depression should be considered in hospital and primary care.

摘要

引言

已知人口统计学因素、症状严重程度和精神病理学,尤其是焦虑和抑郁,会影响哮喘患者的医疗保健利用情况和生活质量。由于抑郁和焦虑通常相互关联,我们试图探讨在控制焦虑影响的情况下,抑郁是否与医疗保健利用和生活质量存在特定关联。

方法

在一项横断面问卷调查研究中,88名哮喘患者(46名女性;年龄范围27 - 70岁)报告了他们的疾病症状、治疗情况,以及焦虑和抑郁情况(医院焦虑抑郁量表,HADS)、总体生活质量(简明健康调查问卷12,SF - 12)和哮喘特异性生活质量(哮喘生活问卷,LAQ)。

结果

虽然未发现焦虑与医疗保健利用之间存在显著关联,但抑郁得分较高与住院次数以及皮质类固醇摄入天数之间的关联显著。此外,即使在控制焦虑的情况下,抑郁得分较高也能解释生活质量问卷所有子量表中的相当大差异。对于焦虑得分,除身体健康外,这些关联具有可比性。

结论

抑郁是哮喘中的一个重要问题,因为它与生活质量和皮质类固醇的摄入密切相关,与住院情况也有一定关联。在医院和初级保健中应考虑对抑郁进行常规筛查。

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