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酒精滥用与自杀行为之间的关联。

The association between alcohol misuse and suicidal behaviour.

作者信息

Brady John

机构信息

General Adult Psychiatry, Holywell Hospital, 60 Steeple Road, Antrim BT41 2RJ, Northern Ireland.

出版信息

Alcohol Alcohol. 2006 Sep-Oct;41(5):473-8. doi: 10.1093/alcalc/agl060. Epub 2006 Aug 4.

Abstract

AIMS

Despite recent small reductions in overall suicide rates, rates among those aged 25-44 have remained high. The aim of this paper was to examine the evidence for a link between alcohol misuse/consumption and suicidal behaviour, explore the reasons for this association, and consider the implications for reducing rates of suicidal behaviour.

METHODS

A medline search was performed to find relevant research evidence.

RESULTS

There is evidence to suggest alcohol misuse predisposes to suicidal behaviour through its depressogenic effects and promotion of adverse life events, and both behaviours may share a common genetic predisposition. Acute alcohol use can also precipitate suicidal behaviours through induction of negative affect and impairment of problem-solving skills, as well as aggravation of impulsive personality traits, possibly through effects on serotonergic neurotransmission.

CONCLUSIONS

Effective interventions for problem drinking may help reduce suicide rates. At a public health level, reducing overall alcohol consumption may be beneficial, and the measures shown to be most effective in this regard are those that aim to restrict availability of alcohol.

摘要

目的

尽管近期总体自杀率略有下降,但25至44岁人群的自杀率仍然很高。本文旨在研究酒精滥用/消费与自杀行为之间联系的证据,探讨这种关联的原因,并考虑其对降低自杀行为发生率的影响。

方法

进行了一项医学文献数据库搜索以查找相关研究证据。

结果

有证据表明,酒精滥用通过其致抑郁作用和促进不良生活事件而使人易患自杀行为,并且这两种行为可能有共同的遗传易感性。急性饮酒还可通过引发负面情绪和损害解决问题的能力,以及可能通过对血清素能神经传递的影响而加剧冲动型人格特质,从而促使自杀行为发生。

结论

针对饮酒问题的有效干预措施可能有助于降低自杀率。在公共卫生层面,减少总体酒精消费量可能有益,而在这方面显示最有效的措施是那些旨在限制酒精供应的措施。

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