眼周手术后的甲状腺相关性眼眶病
Thyroid associated orbitopathy following periocular surgery.
作者信息
Kim Sang June, Kim Byoung Jin, Lee Ha Bum, Tsirbas Angelo, Kazim Michael
机构信息
Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University, College of Medicine, Seoul, Korea.
出版信息
Korean J Ophthalmol. 2006 Jun;20(2):82-6. doi: 10.3341/kjo.2006.20.2.82.
PURPOSE
To descirbe a series of patients in which Thyroid Associated Orbitopathy (TAO) occurred after periocular surgery.
METHODS
A retrospective case review of patients who developed TAO in close temporal association with periocular surgical interventions and presented at the orbital clinic from 1997 to 2004. History of previous thyroid abnormality and the lack of TAO signs and symptoms before surgery were reviewed and analyzed.
RESULTS
Nine patients that developed TAO in association with periocular surgery were identified. All were women with an average age of 59.3years. (range: 45-75 years). The patients divided into two groups. Group 1 consisted of four patients who had previously been diagnosed with Graves' hyperthyroidism (GH). They ranged in age from 48 to 75 years (average: 58.8 years). The diagnosis of GH had been made an average of 50.5 months (range: 12-96 months) before presentation with TAO. Group 2 consisted of five patients who had no previous history of thyroid abnormality. They ranged in age from 45 to 74 years (average: 60.2 years). No patients had any signs or symptoms of TAO before their recent presentation.
CONCLUSIONS
Periocular surgery may lead to local inflammatory events that may contribute to the instigation of TAO in predisposed individuals.
目的
描述一系列在眼周手术后发生甲状腺相关性眼病（TAO）的患者。
方法
对1997年至2004年在眼眶诊所就诊的、与眼周手术干预在时间上密切相关且发生TAO的患者进行回顾性病例分析。回顾并分析既往甲状腺异常病史以及手术前缺乏TAO体征和症状的情况。
结果
确定了9例与眼周手术相关的TAO患者。均为女性，平均年龄59.3岁（范围：45 - 75岁）。患者分为两组。第1组由4例先前被诊断为格雷夫斯甲亢（GH）的患者组成。他们的年龄在48至75岁之间（平均：58.8岁）。在出现TAO之前，GH诊断平均已过去50.5个月（范围：12 - 96个月）。第2组由5例既往无甲状腺异常病史的患者组成。他们的年龄在45至74岁之间（平均：60.2岁）。在近期就诊之前，没有患者有任何TAO的体征或症状。
结论
眼周手术可能导致局部炎症事件，这可能促使易感个体发生TAO。
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