Hurtado Francisco Javier, Nin Nicolás
Department of Pathophysiology, Universidad de la República, Hospital de Clínicas Av. Italia s/n Piso 14, CP11600 Montvideo, Uruguay.
Crit Care Clin. 2006 Jul;22(3):521-9, x. doi: 10.1016/j.ccc.2006.03.005.
The understanding of the pathogenesis of sepsis has substantially changed in past years and continues to improve. New therapeutic options are being developed and incorporated into clinical practice. There are different specific interventions and therapies that benefit patients' outcome. As demonstrated by the early goal-directed therapy strategy, the success of the resuscitation treatment is strongly time dependent. The recognition of severe sepsis should be accompanied without delay by very well defined therapeutic measures. In 2002 the Surviving Sepsis Campaign was introduced with the overall goal of increasing clinicians' awareness and improving outcome in severe sepsis and septic shock.
在过去几年中，对脓毒症发病机制的认识有了实质性的改变，并且仍在不断完善。新的治疗方案正在研发并应用于临床实践。有不同的特异性干预措施和疗法对患者的预后有益。如早期目标导向治疗策略所示，复苏治疗的成功强烈依赖于时间。一旦识别出严重脓毒症，应立即采取明确的治疗措施。2002年发起了拯救脓毒症运动，总体目标是提高临床医生对严重脓毒症和脓毒性休克的认识并改善其预后。
