Kroon J, Botha F S
Department of Community Dentistry, Faculty of Dentistry, University of Pretoria.
SADJ. 2001 Jan;56(1):12-8.
Since the introduction of fluoridated toothpaste more than 30 years ago, it has become by far the most widespread source of fluoride in the world and after fluoridated water the most effective at reducing dental caries. Both the total soluble and the soluble ionic fluoride present in toothpaste are important in determining the effectiveness of the paste as it is important in remineralising demineralised lesions, a characteristic of fluoride which has proven to be the most important in preventing dental caries. The purpose of this study was to evaluate toothpaste currently available to the South African public regarding total soluble and soluble ionic fluoride. A variation of the method used by Grobler et al. (1983) and Du Preez et al. (1993) in previous studies conducted in South Africa was used in preparing the samples for fluoride analysis. Measurements of fluoride concentrations were done using an ionselective electrode. For all toothpaste studied (n=62), large variations occurred for the soluble ionic fluoride (mean = 318.44 microg F/g toothpaste; median = 139.69; standard deviation = 398.77). Correspondingly a mean total soluble fluoride of 848.84 microg F/g toothpaste was found (standard deviation = 189.35; median = 857.38). From this study it can be concluded that fluoride concentrations in toothpaste available to the South African public are in line with those found in the two previous South African studies. In the absence of artificially fluoridated water, toothpaste remains the most cost-effective strategy in the prevention of dental caries in South Africa.
自30多年前引入含氟牙膏以来,它已成为目前世界上分布最为广泛的氟来源,并且是继加氟水之后预防龋齿最有效的方式。牙膏中存在的总可溶性氟和可溶性离子氟对于确定牙膏的功效都很重要,因为这对于使脱矿病变再矿化很重要,而氟的这一特性已被证明在预防龋齿方面最为重要。本研究的目的是评估南非公众目前可获得的牙膏中的总可溶性氟和可溶性离子氟含量。在为氟化物分析制备样品时,采用了Grobler等人(1983年)和Du Preez等人(1993年)在南非此前研究中所使用方法的一种变体。使用离子选择性电极对氟化物浓度进行测量。对于所研究的所有牙膏(n = 62),可溶性离子氟含量存在很大差异(平均值 = 318.44微克氟/克牙膏;中位数 = 139.69;标准差 = 398.77)。相应地,发现总可溶性氟的平均含量为848.84微克氟/克牙膏(标准差 = 189.35;中位数 = 857.38)。从这项研究可以得出结论,南非公众可获得的牙膏中的氟化物浓度与南非此前两项研究中的结果一致。在没有人工加氟水的情况下,牙膏仍然是南非预防龋齿最具成本效益的策略。