Stefaniak J, Kacprzak E, Paul M
Klinika Chorób Pasozytniczych i Tropikalnych AM, 60-355 Poznań, ul. Przybyszewskiego 49.
Wiad Parazytol. 2001;47(3):477-82.
Role of E. granulosus-specific IgG antibody avidity in evaluation of a natural history of the parasite cysts in the liver, duration of infection and immunogenic cysts activity was studied. Thirty-one patients with liver cysts suspected of echinococcosis were examined; E. granulosus infection was finally confirmed by a fine needle aspiration biopsy or surgery in 29 cases (93.5%) and two non-parasitic simple cysts in the liver were diagnosed. E. granulosus-specific IgG antibody was found in 21 patients (67.7%). High IgG avidity values were observed in 14 patients with liver cysts in a degeneration stage confirmed by imaging techniques. Low IgG avidity values were mostly detected in children with hypoechogenic echinococcal cysts being in a recent stage of infection. Determination of anti-E. granulosus immunoglobulin G antibody avidity is a very usefull diagnostic tool for a determination of parasitic cysts activity and their developmental age.
研究了细粒棘球绦虫特异性IgG抗体亲和力在评估肝脏寄生虫囊肿自然史、感染持续时间和免疫原性囊肿活性中的作用。对31例疑似肝包虫病的肝囊肿患者进行了检查；最终通过细针穿刺活检或手术确诊29例（93.5%）为细粒棘球绦虫感染，诊断出2例肝脏非寄生虫性单纯囊肿。21例患者（67.7%）检测到细粒棘球绦虫特异性IgG抗体。在14例经影像学技术证实处于退变阶段的肝囊肿患者中观察到高IgG亲和力值。低IgG亲和力值大多在近期感染阶段的低回声棘球蚴囊肿患儿中检测到。测定抗细粒棘球绦虫免疫球蛋白G抗体亲和力是确定寄生虫囊肿活性及其发育年龄的非常有用的诊断工具。
