[肾小管间质性肾炎伴葡萄膜炎（TINU）综合征]
[TINU syndrome].
作者信息
Svozilková P, Ríhová E, Kontur A, Plsková J, Jeníková D, Kovarík Z
机构信息
Ocní klinika VFN a 1 LF UK, Praha.
出版信息
Cesk Slov Oftalmol. 2006 Jul;62(4):255-62.
PURPOSE
To evaluate our experience with the diagnosis and the treatment of the TINU syndrome. The term TINU syndrome means the intraocular inflammation occurring in association with tubulointerstitial nephritis. The predominance of younger females was established. The uveitis is frequently chronic, moderate, and bilateral. The treatment with immunosuppressive drugs often has positive clinical response.
METHODS
A retrospective study.
RESULTS
Five patients, 4 women and 1 man, have been examined and treated for the TINU syndrome in our Department for Diagnosis and Treatment of Uveitis. The age ranged from 8 to 62 years. The treatment with immunosuppressive drugs caused reduction of the inflammatory reaction and visual acuity improvement.
CONCLUSION
Immunosuppressive drugs were effective in all of our patients suffering from the TINU syndrome. The cooperation between ophthalmologist and nephrologist is crucial for the effective control of the disease activity and for drug regimen optimization.
目的
评估我们对肾小管间质性肾炎伴葡萄膜炎综合征（TINU综合征）的诊断和治疗经验。术语TINU综合征是指与肾小管间质性肾炎相关的眼内炎症。已证实年轻女性居多。葡萄膜炎通常为慢性、中度且双侧发病。免疫抑制药物治疗往往有积极的临床反应。
方法
一项回顾性研究。
结果
在我们的葡萄膜炎诊断与治疗科，对5例TINU综合征患者进行了检查和治疗，其中4例女性，1例男性。年龄范围为8至62岁。免疫抑制药物治疗使炎症反应减轻，视力提高。
结论
免疫抑制药物对我们所有患有TINU综合征的患者均有效。眼科医生和肾病科医生之间的合作对于有效控制疾病活动和优化药物治疗方案至关重要。
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