Wattenberg Lee W
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA.
Cancer Epidemiol Biomarkers Prev. 2006 Aug;15(8):1425-6. doi: 10.1158/1055-9965.EPI-06-0326.
A critical feature in the sequence of events occurring during carcinogenesis is the development of irreversibility. The term "Interlocker" is used here to denote a mechanism by which irreversibility is brought about. The presentation focuses on conceptualizations of such processes. Two will be described below.
致癌过程中发生的一系列事件的一个关键特征是不可逆性的发展。这里使用“联锁器”一词来表示一种导致不可逆性的机制。本报告重点关注此类过程的概念化。下面将描述两种。
