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一种以孤立性延髓麻痹为表现的吉兰-巴雷综合征急性咽颈臂(PCB)变异型。

An acute pharyngeal-cervical-brachial (PCB) variant of Guillain-Barre syndrome presenting with isolated bulbar palsy.

作者信息

Hamidon B B

机构信息

Neurology Unit, Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur.

出版信息

Med J Malaysia. 2006 Jun;61(2):245-7.

Abstract

Acute Guillain-Barre syndrome (GBS) is characterized by an acute onset of limb weakness and areflexia. There are a few rare variants that have been described and one of them is the pharyngeal-cervical-brachial (PCB) variant (oropharynx, neck, and proximal upper limb muscles). However, in this patient, the only presentation was bulbar involvement with fast recovery within days. This is likely to be the milder form of PCB that has rarely been described before. A 19-year-old Malay lady presented with progressive dysphagia associated with nasal voice for one week duration. There was no limb weakness. Examination showed generalized areflexia. Pharyngeal and palatal muscles were markedly weak. Cerebrospinal fluid (CSF) examination showed raised protein level. Nerve conduction studies revealed generalized demyelinating motor polyneuropathy consistent with GBS. The patient fully recovered within three days and was discharged well.

摘要

急性吉兰-巴雷综合征(GBS)的特征是肢体无力和腱反射消失急性发作。已经描述了一些罕见的变异型,其中之一是咽-颈-臂(PCB)变异型(口咽、颈部和近端上肢肌肉)。然而,该患者唯一的表现是延髓受累且在数天内迅速恢复。这可能是以前很少描述过的PCB的较轻形式。一名19岁的马来女性,出现进行性吞咽困难并伴有鼻音,持续一周。无肢体无力。检查显示全身腱反射消失。咽和腭部肌肉明显无力。脑脊液(CSF)检查显示蛋白水平升高。神经传导研究显示符合GBS的全身性脱髓鞘运动性多发性神经病。患者在三天内完全康复并顺利出院。

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