犬肾或肝移植后诱导移植物接受
Induction of graft acceptance after dog kidney or liver transplantation.
作者信息
Ueda Y, Todo S, Eiras G, Furukawa H, Imventarza O, Wu Y M, Oks A, Zeevi A, Oguma S, Starzl T E
机构信息
Department of Surgery, University of Pittsburgh, PA.
出版信息
Transplant Proc. 1990 Feb;22(1):80-2.
Abstract
We have reported that, a short delayed course of intramuscular FK 506 can induce a,donor strain-specific immunologic unresponsiveness to cardiac allograft in rats. Further studies have been performed to determine if this agent can induce graft acceptance after canine renal (KT) or hepatic (OLT) allotransplantation. Preliminary descriptions of these efforts have been published.
摘要
我们已经报道过，肌肉注射FK 506的短期延迟疗程可诱导大鼠对心脏同种异体移植产生供体品系特异性免疫无反应性。我们进一步开展了研究，以确定该药物在犬类肾移植（KT）或肝移植（OLT）同种异体移植后能否诱导移植物被接受。这些研究工作的初步描述已经发表。
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引用本文的文献
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Drugs. 1993 Oct;46(4):746-94. doi: 10.2165/00003495-199346040-00009.
2
FK506 suppression of heart and liver allograft rejection. II: The induction of graft acceptance in rats.FK506对心脏和肝脏同种异体移植排斥反应的抑制作用。II：大鼠移植耐受的诱导
Transplantation. 1990 Nov;50(5):739-44. doi: 10.1097/00007890-199011000-00002.
本文引用的文献
1
Animal research in liver transplantation with special reference to the dog.肝脏移植中的动物研究，特别以狗为例
Semin Liver Dis. 1985 Nov;5(4):309-17. doi: 10.1055/s-2008-1040626.
2
FK 506 for liver, kidney, and pancreas transplantation.用于肝脏、肾脏和胰腺移植的FK 506。
Lancet. 1989 Oct 28;2(8670):1000-4. doi: 10.1016/s0140-6736(89)91014-3.
3
4
Studies of the induction and maintenance of long-term graft acceptance by treatment with FK506 in heterotopic cardiac allotransplantation in rats.
Transplantation. 1987 Dec;44(6):734-8. doi: 10.1097/00007890-198712000-00002.
5
Heterotopic heart transplantation in the rat receiving FK-506 alone or with cyclosporine.单独接受FK-506或与环孢素联合使用时大鼠的异位心脏移植
Transplant Proc. 1987 Oct;19(5 Suppl 6):71-5.
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